205764-47-2Relevant articles and documents
Synthesis of enantioenriched 2-substituted 4-phenylbutylamines by hydrogenolysis of optically pure 6-alkoxy-5,6-dihydro-4H-1,2-oxazines
Buchholz, Monika,Hiller, Florian,Reissig, Hans-Ulrich
, p. 2838 - 2843 (2002)
Lewis acid promoted exchange of the 6-ethoxy group of 6H- 1,2-oxazines 1-3 with (-)-menthol furnished the optically active heterocycles 4-6. Diastereomers 4a and 4b, which could be separated efficiently by chromatography, were excellent substrates for hig