20585-61-9

Basic information

• Product Name: 1-O,2-O,3-O,4-O-Tetrakis(trimethylsilyl)-α-D-arabinopyranose
• Synonyms: 1-O,2-O,3-O,4-O-Tetrakis(trimethylsilyl)-α-D-arabinopyranose
• CAS NO: 20585-61-9
• Molecular Formula: C₁₇H₄₂O₅Si₄
• Molecular Weight: 438.85438
• Mol File: 20585-61-9.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-O,2-O,3-O,4-O-Tetrakis(trimethylsilyl)-α-D-arabinopyranose(CAS DataBase Reference)
• NIST Chemistry Reference: 1-O,2-O,3-O,4-O-Tetrakis(trimethylsilyl)-α-D-arabinopyranose(20585-61-9)
• EPA Substance Registry System: 1-O,2-O,3-O,4-O-Tetrakis(trimethylsilyl)-α-D-arabinopyranose(20585-61-9)

Safety Data

• Hazardous Substances Data: 20585-61-9(Hazardous Substances Data)

Upstream product

• 88434-24-6 marthasteroside A₂ 
• 18156-74-6 1-(Trimethylsilyl)imidazole 
• 75-77-4 chloro-trimethyl-silane 
• 1374792-02-5 (25R)-26-O-β-D-glucopyranosyl-22α-methoxy-5α-furostan-3β,26-diol 3-O-β-D-xylopyranosyl-(1->3)-β-D-glucopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->3)]-β-D-glucopyranosyl-(1->4)-β-D-galactopyranoside 
• 1307292-22-3 (25R)-26-O-β-D-glucopyranosyl-furosta-5,20(22)-diene-1β,3β,26-triol 1-O-[α-L-rhamnopyranosyl-(1->2)-O-α-L-arabinopyranoside] 

Downstream Products

• 87-99-0 XYLITOL 
• 488-82-4 D-Arabitol 
• 1416351-46-6 C₁₂H₁₆O₅ 
• 1416351-59-1 C₂₇H₄₈N₂O₅Si 
• 1416351-57-9 3,4,6-trideoxy-4-azido-2-O-phenoxythiocarbonyl-β-glucopyranoside-(1→4)-benzyl 2-deoxy-2-azido-3-O-triisopropylsilyl-β-xylopyranoside 
• 1416351-56-8 3,4,6-trideoxy-4-azido-β-glucopyranoside-(1→4)-benzyl 2-deoxy-2-azido-3-O-triisopropylsilyl-β-xylopyranoside 
• 1416351-55-7 2-O-acetyl-3,4,6-trideoxy-4-azido-β-glucopyranoside-(1→4)-benzyl 2-deoxy-2-azido-3-O-triisopropylsilyl-β-xylopyranoside 
• 1416351-52-4 benzyl 2-deoxy-2-azido-3-O-triisopropylsilyl-β-xylopyranoside 
• 1416351-53-5 C₂₄H₃₉N₃O₄Si 
• 1416351-50-2 benzyl 4-O-allyl-2-deoxy-2-azido-3-O-triisopropylsilyl-β-xylopyranoside 
• 1416351-51-3 C₂₅H₃₉F₃O₇SSi 
• 1416351-48-8 benzyl 4-O-allyl-3-O-triisopropylsilyl-β-lyxopyranoside 
• 1416351-49-9 C₁₅H₂₀O₅ 
• 1416351-47-7 benzyl 4-O-allyl-2,3-O-carbonyl-β-lyxopyranoside 

Relevant articles and documents

Trifasciatosides A-J, steroidal saponins from Sansevieria trifasciata

Four previously unreported steroidal saponins, trifasciatosides A-D (1-4), three pairs of previously undescribed steroidal saponins, trifasciatosides E-J (5a, b-7a, b) including acetylated ones, together with twelve known compounds were isolated from the n-butanol soluble fraction of the methanol extract of Sansevieria trifasciata. Their structures were elucidated on the basis of detailed spectroscopic analysis, including 1H-NMR, 13C-NMR, 1H-1H correlated spectroscopy (COSY), heteronuclear single quantum coherence (HSQC), heteronuclear multiple bond connectivity (HMBC), total correlated spectroscopy (TOCSY), nuclear Overhauser enhancement and exchange spectroscopy (NOESY), electrospray ionization-time of flight (ESI-TOF)-MS and chemical methods. Compounds 2, 4, and 7a, b exhibited moderate antiproliferative activity against HeLa cells.

Furostanol saponins from the seeds of Allium cepa L.

Allium cepa L. is one of the most widely cultivated and used plants. In addition to its bulb (onion), which is used as food in many cultures, the seeds of A. cepa L. are used as a traditional herbal medicine by the Uygur nationality in China to treat diarrhea and promote blood flow. In a bioactivity-screening, the ethanol extract of seeds of A. cepa L. showed inhibitory effects on protein tyrosine phosphatase 1B (PTP1B) enzyme, with 81.1% inhibition. Phytochemical investigation of the ethanol extract of red onion (Allium cepa L.) seeds led to the isolation of eight new furostanol saponins, named ceparosides E-L (1-8). Their structures were established using 1D and 2D NMR spectroscopy, mass spectrometry and chemical methods. Compounds 1-8 were screened for inhibitory effects on the PTP1B enzyme and cytotoxic activity against five human cells, including HCT-8, Bel-7402, BGC-823, A549 and A2780, but all were found to be inactive.

Desmettianosides A and B, bisdesmosidic furostanol saponins with molluscicidal activity from Yucca desmettiana

Bioactivity-guided separation of the aqueous methanolic extract of Yucca desmettiana leaves, which in a preliminary screening exhibited significant molluscicidal activity, led to the isolation and structure elucidation of two new steroidal saponins (1 and 2). The structures of desmettianosides A and B, identified as bisdesmosidic furostanol glycosides with six and five sugar units, respectively, were established by detailed spectroscopic analyses of their NMR and MS data. Compounds 1 and 2 exhibited high molluscicidal activity against Biomphalaria alexandrina snails with LC100 values of 6 and 11 mg/L, respectively.