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Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2'-FORMYL-BIPHENYL-4-CARBOXYLIC ACID is used as a key intermediate for the synthesis of various pharmaceuticals and agrochemicals, due to its ability to be incorporated into complex molecular structures that can exhibit therapeutic or pesticidal properties.
Used in Material Science:
In the field of material science, 2'-FORMYL-BIPHENYL-4-CARBOXYLIC ACID is used as a building block for the development of new materials, leveraging its structural properties to enhance material characteristics such as stability and functionality.
Used in the Preparation of Liquid Crystals:
2'-FORMYL-BIPHENYL-4-CARBOXYLIC ACID is used as a component in the creation of liquid crystals, which are essential in the display technology of various electronic devices, including watches, calculators, and computer screens.
Used in Organic Light-Emitting Diodes (OLEDs):
2'-FORMYL-BIPHENYL-4-CARBOXYLIC ACID is also used in the production of OLEDs, which are known for their high efficiency, low cost, and potential for flexible display applications, making them valuable in the development of next-generation display technologies.
Used in Organic Synthesis:
2'-FORMYL-BIPHENYL-4-CARBOXYLIC ACID is utilized in organic synthesis for the preparation of various organic compounds, taking advantage of its reactive formyl and carboxylic acid groups to form a wide range of derivatives with diverse applications.

Upstream product

• 40138-16-7 2-formylbenzene boronic acid 
• 1711-02-0 4-iodobenzoic acid chloride 
• 619-58-9 4-iodobenzoic acid 
• 586-76-5 4-Bromobenzoic acid 

Downstream Products

• 223122-43-8 ethyl 2-butyl-3-[4-[2-(2'-formylbiphenyl-4-carbonylamino)ethoxy]phenyl]propionate 

Relevant academic research and scientific papers

Selectivity in the photo-Fenton and photocatalytic hydroxylation of biphenyl-4-carboxylic acid and derivatives (viz. 4-phenylsalicylic acid and 5-phenylsalicylic acid)

The selectivity of hydroxylation of the distal rings of 4-phenylbenzoic acid, 4-phenylsalicylic acid, and 5-phenylsalicylic acid were determined using partial TiO2-mediated photocatalytic degradation and photo-Fenton conditions. This separation of the binding site from the phenyl group being hydroxylated allows a less-biased evaluation. The hydroxylation regiochemistry behaves as qualitatively expected for an electrophilic reaction, given the assumption that 4-carboxyphenyl is a slightly electron-withdrawing substituent. Selectivity for hydroxylation of the distal phenyl in 4- and 5-phenylsalicylic acid is reversed, due to the reversal of the electronic demand, while adsorption to the TiO2 surface is assumed to be analogous for the two structures. Copyright

Mimics of Pincer Ligands: An Accessible Phosphine-Free N-(Pyrimidin-2-yl)-1,2-azole-3-carboxamide Framework for Binuclear Pd(II) Complexes and High-Turnover Catalysis in Water

We report for the first time cyclic phosphine-free "head to tail"N,N,N pincer-like (pincer complexes mimicking) N-(pyrimidin-2-yl)-1,2-azole-3-carboxamide Pd(II) complexes with deprotonated amide groups as high-turnover catalysts (TON up to 106, TOF up to 1.2 × 107 h-1) for cross-coupling reactions on the background of up to quantitative yields under Green Chemistry conditions. The potency of the described catalyst family representatives was demonstrated in Suzuki-Miyaura, Mizoroki-Heck, and Sonogashira reactions on industrially practical examples. Corresponding ligands could be synthesized based on readily available reagents through simple chemical transformations. Within the complex structures, a highly unusual 1,3,5,7-tetraza-2,6-dipalladocane frame could be observed.

Pyrrolobenzodiazepine pyridine carboxamides and derivatives as follicle-stimulating hormone receptor antagonists

This invention provides pyrrolobenzodiazepine pyridine carboxamides selected from those of Formula (1), which act as follicle stimulating hormone receptor antagonists. The invention also provides pharmaceutical compositions and methods of treatment utilizing the compounds of Formulae (1) and (2).

A colored dendrimer as a new soluble support in organic synthesis. Part 1: Suzuki reaction

A new strategy using a colored dendrimer as visible soluble support for organic synthesis has been developed. The efficiency of this new system has been demonstrated by the use of DRHMPA9-CH2OH as the support in a Suzuki coupling reaction. Due to the visibility of the support, following of the reaction has been rendered easier and the purification time of the crude product has been considerably shortened.