206055-89-2

Basic information

• Product Name: [3-(4-FLUORO-PHENYL)-ISOXAZOL-5-YL]-METHANOL
• Synonyms: [3-(4-FLUORO-PHENYL)-ISOXAZOL-5-YL]-METHANOL;5-isoxazolemethanol, 3-(4-fluorophenyl)-;Albb-009791;[3-(4-Fluorophenyl)-1,2-oxazol-5-yl]methanol;[3-(4-fluorophenyl)-5-isoxazolyl]methanol;[3-(4-Fluoro-phenyl)-isoxazol-5-yl]-
• CAS NO: 206055-89-2
• Molecular Formula: C₁₀H₈FNO₂
• Molecular Weight: 193.17
• Mol File: 206055-89-2.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 358.46 °C at 760 mmHg
• Flash Point: 170.591 °C
• Appearance: /
• Density: 1.299 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.554
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: [3-(4-FLUORO-PHENYL)-ISOXAZOL-5-YL]-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(4-FLUORO-PHENYL)-ISOXAZOL-5-YL]-METHANOL(206055-89-2)
• EPA Substance Registry System: [3-(4-FLUORO-PHENYL)-ISOXAZOL-5-YL]-METHANOL(206055-89-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 206055-89-2(Hazardous Substances Data)

Usage

General Description

[3-(4-Fluoro-phenyl)-isoxazol-5-yl]-methanol is a chemical compound with the molecular formula C10H8FNO2. It is an isoxazole derivative that contains a fluorine-substituted phenyl group. [3-(4-FLUORO-PHENYL)-ISOXAZOL-5-YL]-METHANOL is used in organic synthesis and pharmaceutical research as a building block or intermediate for the production of various drugs and bioactive molecules. Its unique structure and functional groups make it a valuable component for designing and synthesizing new pharmaceutical compounds with potential therapeutic effects. Additionally, [3-(4-Fluoro-phenyl)-isoxazol-5-yl]-methanol may also have potential applications in other fields such as material science and agrochemicals due to its versatile reactivity and properties.

InChI:InChI=1/C10H8FNO2/c11-8-3-1-7(2-4-8)10-5-9(6-13)14-12-10/h1-5,13H,6H2

Upstream product

• 42202-95-9 4-fluoro-N-hydroxybenzimidoyl chloride 
• 107-19-7 propargyl alcohol 
• 459-23-4 4-fluorobenzaldoxime 
• 459-57-4 4-fluorobenzaldehyde 
• 6175-54-8 hydroxy-1-propyne 
• 459-23-4 (E)-4-fluorobenzaldehyde oxime 
• 31686-94-9 ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 377052-00-1 ethyl 3-(4-fluorophenyl)isoxazole-5-carboxylate 
• 753479-66-2 [3-(4-fluorophenyl)isoxazol-5-yl]methyl acetate 

Downstream Products

• 1325228-73-6 C₁₂H₉ClFNO₃ 
• 1325228-75-8 C₁₀H₇ClFNO₂ 
• 1239576-23-8 4-chloro-3-(4-fluorophenyl)isoxazole-5-carboxylic acid 
• 1239576-09-0 4-chloro-3-(4-fluorophenyl)-N-((1R,3S)-3-hydroxycyclohexyl)isoxazole-5-carboxamide 
• 1421869-55-7 C₂₅H₂₉FN₄O*ClH 
• 1421869-67-1 C₂₅H₂₈ClFN₄O*ClH 
• 1421869-73-9 C₂₅H₂₈ClFN₄O*ClH 
• 1421869-79-5 C₂₆H₃₁FN₄O₂*ClH 
• 1421869-85-3 C₂₅H₂₈F₂N₄O*ClH 
• 1421869-91-1 C₃₂H₃₃F₃N₄O*ClH 
• 1421869-97-7 C₂₇H₃₃FN₄O*ClH 
• 1421870-03-2 C₂₅H₂₈ClFN₄O*ClH 
• 251912-65-9 3-(4-fluorophenyl)isoxazole-5-carbaldehyde 
• 1421869-61-5 C₂₅H₂₈F₂N₄O*ClH 

Relevant articles and documents

Synthesis of novel 5-(3-alkylquinolin-2-yl)-3-aryl isoxazole derivatives and their cytotoxic activity

The propargyl alcohol on reaction with aldoxime and NaOCl in DCM gave exclusively (3-arylisoxazol-5-yl) methanol 1. The compound 1 was oxidized to an aldehyde 2 followed by reaction with aniline resulted in Schiff's base 3. The compounds 3 were further re

Coumarin phenyl isoxazole derivatives and applications thereof

The invention relates to coumarin phenyl isoxazole derivatives and applications thereof. 4'-hydroxyl chalcone is taken as the raw materials. 4'-hydroxyl chalcone reacts with bromomethyl isoxazole with different substituent groups in the presence of potass

Design and synthesis of a new series of 3,5-disubstituted isoxazoles active against Trypanosoma cruzi and Leishmania amazonensis

Chagas disease and leishmaniasis are neglected tropical diseases (NTDs) endemic in developing countries. Although there are drugs available for their treatment, efforts on finding new efficacious therapies are continuous. The natural lignans grandisin (1)