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20619-12-9

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20619-12-9 Usage

Uses

Monodesmethylchlorpheniramine is an impurity of Chlorpheniramine (C424300), antihistaminic.

Check Digit Verification of cas no

The CAS Registry Mumber 20619-12-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,6,1 and 9 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 20619-12:
(7*2)+(6*0)+(5*6)+(4*1)+(3*9)+(2*1)+(1*2)=79
79 % 10 = 9
So 20619-12-9 is a valid CAS Registry Number.
InChI:InChI=1/C15H17ClN2/c1-17-11-9-14(15-4-2-3-10-18-15)12-5-7-13(16)8-6-12/h2-8,10,14,17H,9,11H2,1H3

20619-12-9 Well-known Company Product Price

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  • Sigma-Aldrich

  • (Y0000437)  Chlorphenamine impurity C  European Pharmacopoeia (EP) Reference Standard

  • 20619-12-9

  • Y0000437

  • 1,880.19CNY

  • Detail

20619-12-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(4-chlorophenyl)-N-methyl-3-pyridin-2-ylpropan-1-amine

1.2 Other means of identification

Product number -
Other names Anti-Nlrb1

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:20619-12-9 SDS

20619-12-9Upstream product

20619-12-9Downstream Products

20619-12-9Relevant academic research and scientific papers

Preparation method of chlorpheniramine maleate impurities

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Paragraph 0030; 0033-0034; 0037-0038; 0041, (2021/04/26)

The invention relates to the technical field of pharmaceutical and chemical quality control, in particular to a preparation method of chlorpheniramine maleate impurities. The preparation method of the chlorpheniramine maleate impurity comprises the following steps: (1) reacting a compound 1 with N-(tert-butyloxycarbonyl)-2-chloroethylamine under an alkaline condition and under the action of a phase transfer catalyst to obtain a compound 2; and (2) reacting the compound 2 with a reducing agent to obtain the chlorpheniramine maleate impurities. The preparation method provided by the invention can be used for directionally synthesizing the European pharmacopoeia EP impurity C in chlorpheniramine maleate, is simple, convenient and feasible in process operation, has the advantages of high yield, high purity, short reaction time and the like, solves the problem of shortage of impurity reference substances, and is more beneficial to quality control on a chlorpheniramine maleate crude drug finished product.

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