206193-26-2Relevant academic research and scientific papers
Synthesis of allenic diols by samarium, diiodide-promoted coupling between alkynyloxiranes and ketones
Aurrecoechea, Jose M.,Alonso, Eva,Solay, Monica
, p. 3833 - 3850 (2007/10/03)
The SmI2-mediated reductive coupling between alkynyloxiranes and ketones provides a new route to 2,3-pentadiene-1,5-diols. The preferred stereochemistry observed in the coupling products is the result of the new C- C bond forming anti with respect to the opening epoxide ring. Yields and diastereoselectivities are dependent on the alkynyloxirane substitution pattern.
