206258-79-9

Basic information

• Product Name: 4-[benzyl-(4-methoxy-benzenesulfonyl)-amino]-8-methyl-quinoline-3-carboxylic acid
• CAS NO: 206258-79-9
• Molecular Weight: 462.526
• Mol File: 206258-79-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[benzyl-(4-methoxy-benzenesulfonyl)-amino]-8-methyl-quinoline-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[benzyl-(4-methoxy-benzenesulfonyl)-amino]-8-methyl-quinoline-3-carboxylic acid(206258-79-9)
• EPA Substance Registry System: 4-[benzyl-(4-methoxy-benzenesulfonyl)-amino]-8-methyl-quinoline-3-carboxylic acid(206258-79-9)

Safety Data

• Hazardous Substances Data: 206258-79-9(Hazardous Substances Data)

Upstream product

• 206258-78-8 4-[benzyl-(4-methoxy-benzenesulfonyl)-amino]-8-methyl-quinoline-3-carboxylic acid ethyl ester 
• 77156-75-3 4-hydroxy-8-methyl-quinoline-3-carboxylic acid ethyl ester 
• 37041-32-0 4-chloro-8-methyl-quinoline-3-carboxylic acid ethyl ester 
• 95-53-4 o-toluidine 

Relevant articles and documents

Synthesis and SAR of bicyclic heteroaryl hydroxamic acid MMP and TACE inhibitors

Potent and selective bicyclic heteroaryl hydroxamic acid MMP and TACE inhibitors were synthesized by a novel convergent route. Selectivity and efficacy versus MMPs and TACE could be controlled by appropriate substitution on the scaffolds and by variation of the P1′ group. Select compounds were found to be effective in in vivo models of arthritis.