206348-97-2

Upstream product

• 206348-96-1 Benzoic acid (R)-1-{2-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-ethyl}-allyl ester 
• 86462-75-1 (Z)-5-<(1,1-dimethylethyl)dimethylsilyloxy>pent-2-en-1-ol 
• 90134-46-6 5-[(tert-butyldimethylsilyl)oxy]pent-2-yn-1-ol 
• 1355509-60-2 (R)-5-(tert-butyldimethylsilyloxy)pent-1-en-3-yl benzoate 
• 930608-32-5 (Z)-5-(tert-butyldimethylsiloxy)pent-2-enyl trichloroacetimidate 
• 206348-94-9 Chloro-acetic acid (R)-1-{2-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-ethyl}-allyl ester 
• 206348-95-0 (R)-5-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-pent-1-en-3-ol 
• 206348-83-6 5-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-pent-1-en-3-ol 
• 57445-90-6 pent-4-ene-1,3-diol 

Downstream Products

• 206348-86-9 (R)-3-benzoyloxy-4-pentene-1-yl 2,3,4,6-tetra-O-benzoyl-α-D-mannopyranoside 

Relevant academic research and scientific papers

The use of COP-OAc in the catalyst-controlled syntheses of 1,3-polyols

An iterative strategy to the 1,3-polyol motif is described. The use of the catalytic asymmetric Overman esterification for the construction of all stereogenic centers is broadly examined as are the sequences to extend the developing polyol chain. The iterative strategies are applied to the total syntheses of rugulactone and polyrhacitides A and B. 1 Introduction 2 Results and Discussion 2.1 Chain Elongation via RCM (Cycle A) 2.2 Total Synthesis of Rugulactone 2.3 Chain Elongation via Ando Olefination (Cycle B) and Total Syntheses of Polyrhacitides A and B 2.4 Useful Variants 3 Conclusions. Georg Thieme Verlag Stuttgart. New York.

Chemoenzymatic synthesis of glycosylated enantiomerically pure 4- pentene 1,2- and 1,3-diol derivatives

1-Dimethylthexylsiloxy-2-chloroacetoxy-4-pentene 2 and 1- dimethylthexylsiloxy-3-chloroacetoxy-4-pentene 3 were saponified with Pseudomonas lipase to give (R)-1-dimethylthexylsiloxy-4-pentene-2-ol (ee=99%) and (S)-2 (ee=99%) and (S)-1-dimethylthexylsiloxy