206362-79-0

Usage

Uses

Used in Pharmaceutical Industry:
4-Chloro-3-fluorophenethyl alcohol is used as an intermediate in the production of pharmaceuticals for its ability to be transformed into a range of active pharmaceutical ingredients. Its unique molecular structure allows for the creation of compounds with specific therapeutic properties, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 4-chloro-3-fluorophenethyl alcohol serves as an intermediate in the synthesis of various agrochemicals, including pesticides and herbicides. Its role in this industry is vital for developing effective solutions to protect crops and enhance agricultural productivity.
Used in Organic Synthesis for Research and Development:
4-Chloro-3-fluorophenethyl alcohol is also used as a key component in organic synthesis for the production of various derivatives. This application is essential for research and development in the chemical industry, where new compounds are continually being explored for potential applications across different fields.
Safety Precautions:
It is important to handle 4-chloro-3-fluorophenethyl alcohol with care due to its potential health hazards. The chemical may cause skin and eye irritation upon contact and can be harmful if ingested or inhaled. Adequate safety measures, such as wearing protective gear and working in well-ventilated areas, should be taken to minimize risks associated with its use.

Upstream product

• 927-74-2 3-Butyn-1-ol 
• 206362-77-8 3-Chloro-4-fluorothiophene-1,1-dioxide 
• 883500-51-4 2-(4-chloro-3-fluorophenyl)acetic acid 

Downstream Products

• 1453853-63-8 4-chloro-3-fluorophenethyl methanesulfonate 
• 1453848-23-1 1-(4-chloro-3-fluorophenethyl)-4-(2-((tetrahydro-2H-pyran-4-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one 

Relevant academic research and scientific papers

3-Chloro-4-fluorothiophene-1,1-dioxide. A new synthetically useful fluorodiene

Simple, three step synthesis of a new fluorine containing diene, 3-chloro-4-fluorothiophene-1,1 -dioxide (4), from commercially available 3-sulpholene (1) has been developed. The synthetic value of compound 4 as a Diels - Alder diene has been demonstrated by its reactions with various type of dienophiles: acetylenes, alkenes, furans, quinone and anthracene. The reactions proceed with high regioselectivity to give good yields of 3-fluoro-4-chloro substituted aromatics or cyclic chlorofluorodienes. In reactions with alkenes, immediate aromatisation often occurs. In some instances, when reacted with a diene, compound 4 behaves as a dienophile.

Novel pyrrolidine or piperidine derivatives having activity for T-type calcium channel

A pyrrolidine or piperidine compound having activity for T - type calcium channel, wherein the pyrrolidine or piperidine compound of Formula 1 according to the present invention has an excellent antagonistic activity to, T-type calcium channel, and can be used as a preventive or therapeutic agent, for pain diseases, or cancer related to cancer, or cancer such as, epilepsy and,hepatic pain, angina. (by machine translation)

Structural hybridization of pyrrolidine-based T-type calcium channel inhibitors and exploration of their analgesic effects in a neuropathic pain model

Highly effective and safe drugs for the treatment of neuropathic pain are urgently required and it was shown that blocking T-type calcium channels can be a promising strategy for drug development for neuropathic pain. We have developed pyrrolidine-based T

Synthesis and biological evaluation of pyrrolidine-based T-type calcium channel inhibitors for the treatment of neuropathic pain

The treatment of neuropathic pain is one of the urgent unmet medical needs and T-type calcium channels are promising therapeutic targets for neuropathic pain. Several potent T-type channel inhibitors showed promising in vivo efficacy in neuropathic pain a