206363-18-0

Basic information

• Product Name: 1,2,5-Oxadiazole-3-carboximidamide,4-amino-N-hydroxy-,2-oxide(9CI)
• Synonyms: 1,2,5-Oxadiazole-3-carboximidamide,4-amino-N-hydroxy-,2-oxide(9CI);3-(N'-hydroxycarbamimidoyl)-4-imino-4,5-dihydro-1,2,5-oxadiazole 2-oxide
• CAS NO: 206363-18-0
• Molecular Formula: C3H5N5O3
• Molecular Weight: 159.1
• Product Categories: AMIDINE
• Mol File: 206363-18-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2,5-Oxadiazole-3-carboximidamide,4-amino-N-hydroxy-,2-oxide(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,5-Oxadiazole-3-carboximidamide,4-amino-N-hydroxy-,2-oxide(9CI)(206363-18-0)
• EPA Substance Registry System: 1,2,5-Oxadiazole-3-carboximidamide,4-amino-N-hydroxy-,2-oxide(9CI)(206363-18-0)

Safety Data

• Hazardous Substances Data: 206363-18-0(Hazardous Substances Data)

Usage

General Description

1,2,5-Oxadiazole-3-carboximidamide,4-amino-N-hydroxy-,2-oxide(9CI) is a chemical compound with potential pharmaceutical applications. It belongs to the class of oxadiazole compounds, which are known for their diverse biological activities. This particular compound has a carboximidamide and amino group, as well as an N-hydroxy-2-oxide moiety, which gives it unique chemical properties. Research suggests that it may have potential as an anticancer or antiviral agent, although further studies are needed to fully understand its biological effects and potential therapeutic applications.

Upstream product

• 206363-17-9 4-amino-1,2,5-oxadiazole-3-carbonitrile 2-oxide 

Relevant articles and documents

C8N12O10: A promising energetic compound with excellent detonation performance and desirable sensitivity

Among energetic materials, there is a significant challenge faced by researchers to seek an optimal balance between high performance and safety. By combination of furoxan and 1,2,4-oxadiazole backbones and C-NO2 moieties, a promising energetic molecule, bis(4-nitro-1,2,5-oxadiazole-2-oxid-3-yl)-azo-1,2,4-oxadiazole (6), was prepared and characterized by IR, multinuclear NMR spectroscopy, elemental analysis, DSC measurements and single crystal X-ray diffraction. It has a high density (1.92 g cm-3), an acceptable thermal stability (182 °C) and a high heat of formation (1188.8 kJ mol-1/2.8 kJ g-1). The calculated detonation performance (D = 9666 m s-1 and P = 42.8 GPa) is comparable to that of CL-20 (9706 m s-1 and 45.2 GPa). More importantly, it shows desirable impact and friction sensitivity (IS: 12 J and FS: 180 N), which is less sensitive than HMX (IS: 7.4 J and FS: 120 N). Furthermore, a detonation test of compound 6 was conducted. The results indicate that compound 6 is more powerful than the commonly used secondary explosive RDX (D = 8795 m s-1 and P = 34.9 GPa). The combination of advanced performances and desirable safety makes this substance a potential secondary explosive.