10,11-Dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-ethanamine, also known as Amitriptyline, is a tricyclic antidepressant belonging to the dibenzazepine class. It is primarily used to treat major depressive disorder, neuropathic pain, and anxiety disorders. Amitriptyline works by inhibiting the reuptake of serotonin and norepinephrine in the brain, thereby increasing their availability in the synaptic cleft and enhancing neurotransmission. This action helps to alleviate symptoms of depression and anxiety. The chemical structure consists of a dibenz[b,f]azepine core with a 10,11-dihydro ring, an ethanamine side chain, and three methyl groups attached to the nitrogen atoms. It is an important medication in the management of mood disorders and neuropathic pain, although it may also cause side effects such as drowsiness, dry mouth, and weight gain.
2064-21-3
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Basic information
- Product Name: 10,11-Dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-ethanamine
- Synonyms: G-31002
- CAS NO:2064-21-3
- Molecular Formula: C19H24N2
- Molecular Weight: 280.40726
- EINECS: N/A
- Product Categories: N/A
- Mol File: 2064-21-3.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 394.5°C at 760 mmHg
- Flash Point: 175°C
- Appearance: /
- Density: 1.049g/cm3
- Vapor Pressure: 1.97E-06mmHg at 25°C
- Refractive Index: 1.579
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 10,11-Dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-ethanamine(CAS DataBase Reference)
- NIST Chemistry Reference: 10,11-Dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-ethanamine(2064-21-3)
- EPA Substance Registry System: 10,11-Dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-ethanamine(2064-21-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 2064-21-3(Hazardous Substances Data)
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Check Digit Verification of cas no
The CAS Registry Mumber 2064-21-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,0,6 and 4 respectively; the second part has 2 digits, 2 and 1 respectively.Calculate Digit Verification of CAS Registry Number 2064-21:
(6*2)+(5*0)+(4*6)+(3*4)+(2*2)+(1*1)=53
53 % 10 = 3
So 2064-21-3 is a valid CAS Registry Number.
InChI:InChI=1/C19H24N2/c1-15(14-20(2)3)21-18-10-6-4-8-16(18)12-13-17-9-5-7-11-19(17)21/h4-11,15H,12-14H2,1-3H3
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10,11-Dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-ethanamine
