20641-27-4Relevant academic research and scientific papers
O-allylated pudovik and passerini adducts as versatile scaffolds for product diversification
Arseniyadis, Stellios,El Ka?m, Laurent,Kerim, Mansour Dole,Katsina, Tania,Cattoen, Martin,Fincias, Nicolas
supporting information, p. 12514 - 12525 (2020/11/10)
The palladium-catalyzed O-allylation of α-hydroxyphosphonates and α-hydroxyamides obtained from Pudovik and Passerini multicomponent reactions has allowed interesting and highly straightforward access to a variety of building blocks for product diversific
Palladium-catalysed O-Allylation of α-Hydroxyphosphonates: An Expedient Entry into Phosphono-oxaheterocycles
Kerim, Mansour Dolé,Cattoen, Martin,Fincias, Nicolas,Dos Santos, Aurélie,Arseniyadis, Stellios,El Ka?m, Laurent
supporting information, p. 449 - 454 (2017/12/04)
We report here an unprecedented palladium-catalysed O-allylation of α-hydroxyphosphonates. The method was eventually included in a sequential Pudovik/Tsuji-Trost type O-allylation/Ring-Closing Metathesis to afford a variety of phosphorylated heterocycles
Copper-catalyzed synthesis of α-hydroxy phosphonates from H-phosphonates and alcohols or ethers
Zhao, Zengxiang,Xue, Wanhua,Gao, Yuxing,Tang, Guo,Zhao, Yufen
supporting information, p. 713 - 716 (2013/05/09)
Easy PC: α-Hydroxy phosphonates were synthesized by copper/tert-butyl hydroperoxide (TBHP)-catalyzed oxidative addition reactions of H-phosphonates with alcohols or ethers. Diverse α-hydroxy phosphonates were obtained from substituted benzyl alcohols or alkyl alcohols and alkyl ethers in moderate to good yields. Copyright
Mechanistic approach for expeditious and solvent-free synthesis of α-hydroxy phosphonates using potassium phosphate as catalyst
Kulkarni, Makarand A.,Lad, Uday P.,Desai, Uday V.,Mitragotri, Satish D.,Wadgaonkar, Prakash P.
, p. 148 - 152 (2013/04/24)
An extremely simple, high yielding, highly rapid and solvent-free protocol has been described for hydrophosphylation of aldehydes using potassium phosphate as catalyst. Easy commercial availability of the reusable catalyst, operational simplicity at ambie
Synthesis, characterizations, and crystal structures of α-hydroxyphosphonic acid esters
Fang, Hua,Chen, Weizhu,Hong, Bihong,Zhao, Yufen,Fang, Meijuan
experimental part, p. 2182 - 2193 (2010/12/25)
This article describes the synthesis of -hydroxyphosphonic acid esters using the Pudovik reaction. IR, 1H NMR, 13C NMR, 31P NMR, MS, and elemental analysis were employed to confirm their structures. X-ray structure analysi
Mercaptophosphonate compounds as broad-spectrum inhibitors of the metallo-β-lactamases
Lassaux, Patricia,Hamel, Matthieu,Gulea, Mihaela,Delbrück, Heinrich,Mercuri, Paola Sandra,Horsfall, Louise,Dehareng, Dominique,Kupper, Micha?l,Frère, Jean-Marie,Hoffmann, Kurt,Galleni, Moreno,Bebrone, Carine
supporting information; experimental part, p. 4862 - 4876 (2010/10/18)
Although commercialized inhibitors of active site serine β-lactamases are currently used in coadministration with antibiotic therapy, no clinically useful inhibitors of metallo-β-lactamases (MBLs) have yet been discovered. In this paper, we investigated t
Straightforward synthesis of a new series of α-(arylamino thiocarbonyloxy) hydrocarbylphosphonates
Li, Jian-Ping,Zhu, Jun-Ge,Liu, Rui-Jie,Cui, Feng-Ling,Liu, Ping,Liu, Guo-Sheng
, p. 5 - 8 (2008/12/21)
A convenient, straightforward, two-step reaction of α- hydroxyhydrocarbylphosphonates with arylisothiocyanates in the presence of catalytic amounts of sodium methoxide in 1,2-dichloroethane as solvent produced various new α-(arylamino thiocarbonyloxy) hyd
