20641-34-3Relevant academic research and scientific papers
Asymmetric hydrogenation of α-keto phosphonates with chiral palladium catalysts
Goulioukina, Nataliya S.,Bondarenko, Grigorii N.,Bogdanov, Alexei V.,Gavrilov, Konstantin N.,Beletskaya, Irina P.
, p. 510 - 515 (2009)
Under atmospheric hydrogen pressure, a catalytic amount of palladium(II) trifluoroacetate and (R)-MeO-BIPHEP in 2,2,2-trifluoroethanol promoted the asymmetric hydrogenation of diisopropyl α-keto phosphonates 1 to afford the corresponding α-hydroxy phospho
Mercaptophosphonate compounds as broad-spectrum inhibitors of the metallo-β-lactamases
Lassaux, Patricia,Hamel, Matthieu,Gulea, Mihaela,Delbrück, Heinrich,Mercuri, Paola Sandra,Horsfall, Louise,Dehareng, Dominique,Kupper, Micha?l,Frère, Jean-Marie,Hoffmann, Kurt,Galleni, Moreno,Bebrone, Carine
supporting information; experimental part, p. 4862 - 4876 (2010/10/18)
Although commercialized inhibitors of active site serine β-lactamases are currently used in coadministration with antibiotic therapy, no clinically useful inhibitors of metallo-β-lactamases (MBLs) have yet been discovered. In this paper, we investigated t
