206432-29-3Relevant academic research and scientific papers
Combinatorial synthesis of dihydropyridone libraries and their derivatives
Creswell, Mark W.,Bolton, Gary L.,Hodges, John C.,Meppen, Malte
, p. 3983 - 3998 (2007/10/03)
Polymer-supported quench methodology has been used for parallel purification of combinatorial libraries of dihydropyridones and their derivatives. The dihydropyridone scaffold was assembled via a solution phase Lewis acid catalyzed, hetero-Diels-Alder reaction. Further modifications allow for the rapid generation of subsequent aminopiperidine and acylaminopiperidine libraries utilizing a library from library approach.
