206434-83-5Relevant academic research and scientific papers
Novel nonsteroidal selective estrogen receptor modulators. Carbon and heteroatom replacement of oxygen in the ethoxypiperidine region of raloxifene
Schmid, Christopher R.,Sluka, James P.,Duke, Kristen M.,Glasebrook, Andrew W.
, p. 523 - 528 (2007/10/03)
Compounds were synthesized where oxygen in the ethoxypiperidine region of raloxifene is replaced with carbon, sulfur, or nitrogen linkages. Thia- and aza-substituted compounds were prepared by novel methodology. The compounds were evaluated in vitro as se
Substituted benzo(b)thiophene compounds having activity as selective estrogen receptor modulators
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, (2008/06/13)
The present invention provides compounds with nitrogen, sulfur or carbon linked basic side chains of formula where R1and R2are independently hydrogen, halo, hydroxy, alkoxy, alkylcarbonyloxy, alkoxycarbonyl, alkoxycarbonyloxy, arylca
