206443-06-3 Usage
Uses
Used in Enzyme Activity Assays:
4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) is used as a substrate for the determination of galactose-6-sulfate sulfatase activity. It is cleaved by the enzyme to release the fluorescent moiety 4-MU, allowing for the quantification of enzyme activity.
Used in Lysosomal Storage Disorder Diagnosis:
4-MU-Gal-6S is used in the diagnosis of Mucopolysaccharidosis IV A (Morquio disease type A), a lysosomal storage disorder characterized by a deficiency of GALNS enzyme activity. The substrate can be used to assess GALNS activity in a very small blood volume, helping to determine the extent of deficiency.
Used in Research and Development:
4-MU-Gal-6S is utilized in research and development for the study of lysosomal storage disorders, enzyme kinetics, and the development of potential therapeutic agents targeting GALNS deficiency. Its fluorescence properties make it a valuable tool for monitoring enzyme activity and screening for potential enzyme modulators.
Check Digit Verification of cas no
The CAS Registry Mumber 206443-06-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,6,4,4 and 3 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 206443-06:
(8*2)+(7*0)+(6*6)+(5*4)+(4*4)+(3*3)+(2*0)+(1*6)=103
103 % 10 = 3
So 206443-06-3 is a valid CAS Registry Number.
InChI:InChI=1/C16H18O11S.Na/c1-7-4-12(17)26-10-5-8(2-3-9(7)10)25-16-15(20)14(19)13(18)11(27-16)6-24-28(21,22)23;/h2-5,11,13-16,18-20H,6H2,1H3,(H,21,22,23);/q;+1/p-1/t11?,13-,14-,15-,16+;/m0./s1/rC16H17NaO11S/c1-7-4-12(18)26-10-5-8(2-3-9(7)10)25-16-15(21)14(20)13(19)11(27-16)6-24-29(22,23)28-17/h2-5,11,13-16,19-21H,6H2,1H3/t11?,13-,14-,15-,16+/m0/s1
