20646-39-3Relevant academic research and scientific papers
Demethoxycarbonylation of Methyl 2,5- and Methyl 3,6-Dialkyl-1H-azepine-1-carboxylates: Formation and Characterization of 2H-,3H- and 4H-Azepines
Satake, Kyosuke,Okuda, Ryoichi,Hashimoto, Michiaki,Fujiwara, Yasusi,Okamoto, Hideki,et al.
, p. 1753 - 1758 (2007/10/02)
Demethoxycarbonylation of methyl 2,5-di-tert-butyl-1H-azepine-1-carboxylate using 1,8-diazabicycloundec-7-ene (DBU) gave 3H-azepines.Under similar conditions, methyl 3,6-di-tert-butyl-1H-azepine-1-carboxylate gave not only the 3H-azepine but also the isomerized 2H- and 4H-azepines.Application of the reaction to dimethyl and diisopropyl substituted 1H-azepines showed that bulky alkyl group substitution stabilized the seven-membered azatriene system.The thermal behaviour of the di-tert-butyl substituted azepines is discussed.
A NEW REACTION OF NITRENE WITH 1H-AZEPINE DERIVATIVES: A FORMATION OF 2,6-DIAZABICYCLOOCTADIENE AND 2,8-DIAZABICYCLOOCTADIENE
Kumagai, Tsutomu,Satake, Kyosuke,Kidoura, Kazuo,Mukai, Toshio
, p. 2275 - 2278 (2007/10/02)
The formation of two diazabicyclooctadienes (2 and 3) is elucidated by the intermediacy of azahomoazepine.
