20657-38-9Relevant academic research and scientific papers
Synthesis of a novel silicon-bridged [2.2]metacyclophan-9-ene and its photolytic transannular reaction
Oba, Makoto,Iida, Minoru,Nagoya, Tomoki,Nishiyama, Kozaburo
, p. 1151 - 1153 (2006)
A novel [2.2]metacyclophane in which two benzene rings are linked together with a carbon-carbon double bond and a disilane unit was prepared. Photolysis of the cyclophane in the presence of oxygen afforded the 4,5-dihydro-4,5- disilapyrene derivative via
Copper-catalysed, diboron-mediated: Cis -dideuterated semihydrogenation of alkynes with heavy water
Han, Xiaowei,Hu, Jiefeng,Chen, Cheng,Yuan, Yu,Shi, Zhuangzhi
supporting information, p. 6922 - 6925 (2019/06/18)
Methods to incorporate deuterium atoms into organic molecules are valuable for the pharmaceutical industry. Here, we found that diboron reagents can efficiently mediate the transfer of two D atoms from heavy water directly onto alkynes through copper-catalysed cis-selective semihydrogenation. Avoiding the use of costly and flammable D2 gas, this safe and practical process can proceed with excellent chemoselectivity and stereoselectivity. Utilizing the present method as the key step, the formal asymmetric total synthesis of d2-deuterium-labeled cis-combretastatin A4 is demonstrated. Mechanistic studies suggest that monoborylation of alkynes is the key step for this semihydrogenation process.
Synthesis of a guanidine NHC complex and its application in borylation reactions
Tai, Chia-Cheng,Yu, Ming-Shiuan,Chen, Yi-Lin,Chuang, Wen-Hang,Lin, Ting-Hua,Yap, Glenn P. A.,Ong, Tiow-Gan
supporting information, p. 4344 - 4346 (2014/04/17)
Synthesis of guanidine-linked NHC can be achieved easily through reacting amino-NHC with carbodiimide. Subsequently, guanidine-NHC Ag and Cu complexes were isolated and fully characterized. These Cu complexes are found to be versatile catalysts for hydroboration, semihydrogenation and carboboration of alkynes in a highly stereo- and regioselective fashion.
Ruthenium(II) porphyrin catalyzed cyclopropanation of alkenes with tosylhydrazones
Zhang, Jun-Long,Hong Chan, Philip Wai,Che, Chi-Ming
, p. 8733 - 8737 (2007/10/03)
The diastereoselective ruthenium(II) porphyrin catalyzed cyclopropanation of a variety of alkenes with aryl diazomethanes generated in situ from stable tosylhydrazone derivatives, was achieved in good to excellent yields (up to 92%) and product turnovers.
MAGNETIC COUPLING BETWEEN TWO PHENOXYL RADICALS ATTACHED TO THE PHENYL RINGS OF CIS- AND TRANS-STILBENES
Mitsumori, Teruyuki,Koga, Noboru,Iwamura, Hiizu
, p. 43 - 49 (2007/10/02)
Magnetic coupling between two sterically protected phenoxyl radicals through the cis- and trans-stilbene chromophores was studied by means of their EPR fine structures.While the zero-field splitting parameters D, which are governed by the magnitude of dip
