20661-64-7Relevant academic research and scientific papers
PTP-1B inhibitors: Cyclopenta[d][1,2]-oxazine derivatives
Cho, Sung Yun,Baek, Ji Yoen,Han, Sang Sub,Kang, Seung Kyu,Ha, Jae Du,Ahn, Jin Hee,Lee, Jae Don,Kim, Kwang Rok,Cheon, Hyae Gyeong,Rhee, Sang Dal,Yang, Sung Don,Yon, Gyu Hwan,Pak, Chwang Siek,Choi, Joong-Kwon
, p. 499 - 502 (2007/10/03)
A series of novel cyclopenta[d][1,2]-oxazine derivatives was prepared and evaluated for their inhibitory activity toward protein tyrosine phosphatase 1B (PTP-1B). Compound 6s was found to be an inhibitor of PTP-1B with nanomolar IC50 value and
