20667-04-3

Basic information

• Product Name: 2-ethylhexane-1,2-diol
• CAS NO: 20667-04-3
• Molecular Formula: C₈H₁₈O₂
• Molecular Weight: 146.2273
• Mol File: 20667-04-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 226°C at 760 mmHg
• Flash Point: 97.9°C
• Density: 0.939g/cm³
• Vapor Pressure: 0.0166mmHg at 25°C
• Refractive Index: 1.453
• CAS DataBase Reference: 2-ethylhexane-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethylhexane-1,2-diol(20667-04-3)
• EPA Substance Registry System: 2-ethylhexane-1,2-diol(20667-04-3)

Safety Data

• Hazardous Substances Data: 20667-04-3(Hazardous Substances Data)

Upstream product

• 1632-16-2 2-ethyl-1-hexene 
• 123-05-7 d,l-2-ethylhexanal 
• 89000-61-3 4-butyl-4-ethyl-2-(heptan-3-yl)-1,3-dioxolane 
• 105357-31-1 1,2-diacetoxy-2-ethylhexane 
• 1436-35-7 (±)-2-butyl-2-ethyloxirane 
• 645-62-5 2-ethylhexenal 
• 26578-61-0 2-ethyl-2-hydroxy-hexanal 

Downstream Products

• 123-05-7 d,l-2-ethylhexanal 

Relevant articles and documents

Development of an Enzymatic Process for the Production of (R)-2-Butyl-2-ethyloxirane

An epoxide resolution process was rapidly developed that allowed access to multigram scale quantities of (R)-2-butyl-2-ethyloxirane 2 at greater than 300 g/L reaction concentration using an easy-to-handle and store lyophilized powder of epoxide hydrolase from Agromyces mediolanus. The enzyme was successfully fermented on a 35 L scale and stability increased by downstream processing. Halohydrin dehalogenases also gave highly enantioselective resolution but were shown to favor hydrolysis of the (R)-2 epoxide, whereas epoxide hydrolase from Aspergillus Niger instead provided (R)-7 via an unoptimized, enantioconvergent process.

Palladium on Charcoal Catalyzed 3,4-Hydroperoxidation of α-Substituted Enals with Triethylsilane and Water

Aldehyde α-hydroperoxides can be accessed from α-substituted acroleins with triethylsilane and water under Pd/C catalysis and aerobic conditions. The reaction is composed of a Pd/C-catalyzed conjugate reduction step and a hydroperoxidation step. The hydroperoxidation takes place via autoxidation of sufficiently stable enols formed in situ by transfer hydrogenation. Upon reduction, 2,2-disubstituted 1,2-diols are obtained directly from aldehydes.

Oxidative Cleavage of Olefins into Carboxylic Acids with Hydrogen Peroxide by Tungstic Acid

A facile conversion of olefins into carboxylic acids could be achieved by using aqueous hydrogen peroxide (35percent-H2O2) in the presence of catalytic amounts of tungstic acid (5 wtpercent).The oxidation was markedly influenced by the acidity of the reaction medium, and it was found to proceed favorably under a weak acidic condition (pH 4-5).