206866-63-9

Upstream product

• 108869-64-3 2-O-acetyl-3,4,6-tri-O-benzyl-α-D-mannopyranosyl trichloroacetimidate 
• 206866-62-8 (2R,4aR,6S,7R,8R,8aS)-6-{(2R,3S,4R,5R,6S)-5-Azido-4-benzyloxy-2-benzyloxymethyl-6-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-tetrahydro-pyran-3-yloxy}-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxine-7,8-diol 
• 174077-02-2 dimethylthexylsilyl 3,6-di-O-benzyl-2-deoxy-2-azido-β-D-glucopyranoside 
• 206866-61-7 2,3-di-O-acetyl-4,6-O-benzylidene-D-glucopyranosyl trichloroacetimidate 
• 206866-68-4 Acetic acid (2R,4aR,6S,7R,8S,8aR)-8-acetoxy-6-{(2R,3S,4R,5R,6S)-5-azido-4-benzyloxy-2-benzyloxymethyl-6-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-tetrahydro-pyran-3-yloxy}-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl ester 

Downstream Products

• 206866-69-5 C₇₀H₈₅N₃O₁₆Si 
• 206866-64-0 C₇₀H₈₇N₃O₁₆Si 
• 206866-70-8 C₇₇H₉₁N₃O₁₆Si 

Relevant academic research and scientific papers

A versatile strategy for the synthesis of complex type N-glycans: Synthesis of diantennary and bisected diantennary oligosaccharides1

Based on readily available glucose, 2-azido-glucose, mannose, and N- phthaloyllactosamine building blocks 5, 6, 8, and 13 a highly versatile strategy for the synthesis of complex type and bisected complex type N- glycan residues is established; this is demonstrated for the synthesis of nonasaccharide 1 and decasaccharide 2, respectively. The glucose residue g finally provides regioselective access to the 3-, 4-, and/or 6-hydroxy groups for antenna attachment, introduction of the bisecting N-acetylglucosamine residue, and epimerisation at C-2 in order to generate the required β- linked mannosyl residue c.