20688-37-3 Usage
Uses
Used in Pharmaceutical Industry:
(3S,4S)-4-AMINO-1,1-DIOXO-TETRAHYDRO-1LAMBDA6-THIOPHEN-3-OL is used as an antibiotic medication for treating a variety of bacterial infections. Its chemical structure and properties make it effective against infections such as respiratory, skin, and urinary tract infections. As a member of the penicillin class, it plays a crucial role in the medical field for combating bacterial diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 20688-37-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,6,8 and 8 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 20688-37:
(7*2)+(6*0)+(5*6)+(4*8)+(3*8)+(2*3)+(1*7)=113
113 % 10 = 3
So 20688-37-3 is a valid CAS Registry Number.
InChI:InChI=1/C4H9NO3S/c5-3-1-9(7,8)2-4(3)6/h3-4,6H,1-2,5H2/t3-,4-/m1/s1
20688-37-3Relevant articles and documents
Structure-activity studies of cyclic ketone inhibitors of the serine protease plasmin: Design, synthesis, and biological activity
Xue, Fengtian,Seto, Christopher T.
, p. 8467 - 8487 (2008/02/05)
Three series of cyclic ketone inhibitors were synthesized and evaluated against the serine protease plasmin. Peptide inhibitors that incorporated 3-oxotetrahydrofuran and 3-oxotetrahydrothiophene 1,1-dioxide groups had the highest activities. Alkylamino substituents, which were designed to bind in the S1 subsite of plasmin, were attached to the inhibitors. Compounds 5c and 5g, which incorporated 6-aminohexyl substituents, were found to be optimal and demonstrated IC50 values in the low micromolar range. Incorporating conformationally constrained peptide segments into the inhibitors did not improve their activities.
