20688-91-9Relevant academic research and scientific papers
Synthesis of glycose carbamides and evaluation of the induction of erythroid differentiation of human erythroleukemic K562 cells
Landi, Martina,Catelani, Giorgio,D'Andrea, Felicia,Ghidini, Eleonora,Amari, Gabriele,Paola, Puccini,Bianchi, Nicoletta,Gambari, Roberto
experimental part, p. 745 - 754 (2009/09/27)
A series of carbamides derived from 1,2:5,6-di-O-isopropylidene-d-gluco- (1) and d-allofuranose (3) as well as their 5,6-O-deprotected analogues (2 and 4) and methyl 3,4-O-isopropylidene-α- and β-d-galactopyranosides (5 and 6) have been prepared in order to evaluate their ability to induce erythroid differentiation of human erythroleukemic K562 cells. Twenty out of 51 carbamides tested exhibit an appreciable activity as inducers of erythroid differentiation and have been fully characterized and described.
A sugar aminoacid for the development of multivalent ligands for Escherichia coli 0157 verotoxin
Gibson, Darren,Homans, Steven W.,Field, Robert A.
body text, p. 730 - 732 (2009/10/10)
Functionalised carbohydrates for incorporation into multivalent ligands for the Escherichia coli 0157 verotoxin are highly desirable. Here, we report the synthesis of a sugar aminoacid based on the known Gal-α-1,4-Gal ligand for verotoxin in eight steps a
