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CAS

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206883-01-4

5-(3-amino-2,6-dichlorobenzyloxy)isoquinoline is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 206883-01-4 Structure

  • Basic information

    1. Product Name: 5-(3-amino-2,6-dichlorobenzyloxy)isoquinoline
    2. Synonyms: 5-(3-amino-2,6-dichlorobenzyloxy)isoquinoline
    3. CAS NO:206883-01-4
    4. Molecular Formula:
    5. Molecular Weight: 319.19
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 206883-01-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 5-(3-amino-2,6-dichlorobenzyloxy)isoquinoline(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5-(3-amino-2,6-dichlorobenzyloxy)isoquinoline(206883-01-4)
    11. EPA Substance Registry System: 5-(3-amino-2,6-dichlorobenzyloxy)isoquinoline(206883-01-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 206883-01-4(Hazardous Substances Data)

206883-01-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 206883-01-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,6,8,8 and 3 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 206883-01:
(8*2)+(7*0)+(6*6)+(5*8)+(4*8)+(3*3)+(2*0)+(1*1)=134
134 % 10 = 4
So 206883-01-4 is a valid CAS Registry Number.

206883-01-4Relevant articles and documents

Studies on anti-Helicobacter pylori agents. Part 1: Benzyloxyisoquinoline derivatives

Yoshida, Yoshiki,Barrett, David,Azami, Hidenori,Morinaga, Chizu,Matsumoto, Satoru,Matsumoto, Yoshimi,Takasugi, Hisashi

, p. 2647 - 2666 (2011/05/18)

The synthesis and optimization of the anti-Helicobacter pylori activity of a novel series of benzyloxyisoquinoline derivatives that was discovered by a random screening process, are described. In the in vitro assay, compound 10c containing a 3-acetamido-2,6-dichlorobenzyl substituent was found to have extremely potent activity against H. pylori and no activity against other common bacteria. The anti-H. pylori activity of 10c was superior to that of amoxicillin (AMPC) (1) and clarithromycin (CAM) (2). However, 10c did not show in vivo efficacy in a mouse infection model; a feature attributed to the lack of strong bactericidal activity at short contact times. (C) 1999 Elsevier Science Ltd.

Discovery of a novel benzyloxyisoquinoline derivative with potent anti- Helicobacter pylori activity

Yoshida, Yoshiki,Barrett, David,Azami, Hidenori,Morinaga, Chizu,Matsumoto, Yoshimi,Takasugi, Hisashi

, p. 1897 - 1902 (2007/10/03)

The synthesis and in vitro optimization of the anti-Helicobacter pylori activity of a novel series of benzyloxyisoquinoline derivatives discovered by a random screening process, are described. FR180102 (7f), having a 3- acetamido-2,6-dichlorobenzyl moiety, was found to have extremely potent activity against H. pylori and no effect against a series of common Gram- positive and Gram-negative bacteria.

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