206976-18-3Relevant articles and documents
Synthesis of New 4-Nitrosophenyl-1,4-dihydropyridines of Pharmacological Interest
Santander-G,Nunez-Vergara, Luis J.,Squella,Navarrete-Encina
, p. 2781 - 2784 (2003)
The synthesis and characterization of a series of 4-nitro-sophenyl-1,4- dihydropyridines derived from the respective nitro compounds of pharmacological interest is described. The complete synthetic pathway is based on the classical Hantzsch 1,4-dihydropyridine synthesis to obtain the nitrophenyl 1,4-dihydropyridines in a first step, followed by chemical reduction of the nitro compound to the corresponding hydroxylamine and further oxidation to the nitroso derivative. The synthesis and characterization of the compounds is described.