206982-88-9Relevant academic research and scientific papers
α-Aroylidineketene dithioacetal chemistry: CuI catalyzed synthesis of 2-styryl benzimidazoles enroute to regioselective hydrothiolation
Dhanalakshmi, Pandi,Shanmugam, Sivakumar
, p. 6300 - 6314 (2015/08/03)
Abstract Reactivity of α-aroylidineketene dithioacetals 2 was investigated to synthesize novel 2-styrylbenzimidazole derivatives 4 and their hydrothiolated product 2-(2-(methylthio)-2-arylethyl)-1H-benzo[d]imidazoles 5 has been reported. Compounds 4 and 5
From a Multipotent Stilbene to Soluble Epoxide Hydrolase Inhibitors with Antiproliferative Properties
Buscato, Estel.La,Buettner, Dominik,Brueggerhoff, Astrid,Klingler, Franca-Maria,Weber, Julia,Scholz, Bastian,Zivkovic, Aleksandra,Marschalek, Rolf,Stark, Holger,Steinhilber, Dieter,Bode, Helge B.,Proschak, Ewgenij
supporting information, p. 919 - 923 (2013/07/27)
Inspired by nature: Natural product isopropylstilbene was identified as an inhibitor of soluble epoxide hydrolase exhibiting antiproliferative properties. Following the natural product inspired design approach, a library of (E)-styryl-1H-benzo[d]imidazoles was synthesized and evaluated with recombinant enzyme and on several cancer cell lines. Copyright
