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SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 is a non-denaturing, anionic detergent derived from the bile acid, Cholate, which is produced in the liver during cholesterol breakdown. It is commonly used as a biochemical solubilizing agent for the extraction and reconstitution of membrane proteins and protein complexes. Sodium cholate hydrate possesses the ability to downregulate cholesterol-7-α-hydroxylase, a rate-limiting step in bile acid synthesis, and is involved in various applications across different industries.

206986-87-0

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206986-87-0 Usage

Uses

Used in Biochemical Research:
SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 is used as a biochemical solubilizing agent for the extraction of membrane proteins. It serves as a non-denaturing detergent, allowing for the preservation of protein structure and function during the extraction process.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 is used as an ingredient in the formulation of drugs, particularly those targeting the liver and cholesterol-related conditions. Its ability to downregulate cholesterol-7-α-hydroxylase makes it a valuable component in the development of therapies for cholesterol management.
Used in Material Science:
SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 is utilized in the study to assess the infiltration of pressurized promoter solutions in mesoporous silica. Its role as a solubilizing agent aids in understanding the interaction between the promoter solutions and the silica material, contributing to the advancement of material science research.
Used in Agricultural Research:
In agricultural research, SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 can be employed as a tool to study the interaction of various compounds with membrane proteins in plants, which can lead to the development of more effective pesticides or fertilizers.
Used in Environmental Science:
SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 can be used in environmental science applications to study the interaction of pollutants with membrane proteins in microorganisms, helping to develop strategies for bioremediation and pollution control.

Biochem/physiol Actions

Reduction in 12-α hydroxylase activity leads to low levels of cholic acid in liver disease.

Check Digit Verification of cas no

The CAS Registry Mumber 206986-87-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,6,9,8 and 6 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 206986-87:
(8*2)+(7*0)+(6*6)+(5*9)+(4*8)+(3*6)+(2*8)+(1*7)=170
170 % 10 = 0
So 206986-87-0 is a valid CAS Registry Number.
InChI:InChI=1/C24H40O4.Na/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26;/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15+,16-,17-,18?,19?,20-,22?,23+,24-;/m1./s1

206986-87-0 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (A17074)  Sodium cholate hydrate, 99%   

  • 206986-87-0

  • 10g

  • 319.0CNY

  • Detail
  • Alfa Aesar

  • (A17074)  Sodium cholate hydrate, 99%   

  • 206986-87-0

  • 50g

  • 954.0CNY

  • Detail
  • Sigma

  • (27029)  Sodiumcholatehydrate  ≥97.0% (dried material, NT)

  • 206986-87-0

  • 27029-100G-F

  • 1,542.06CNY

  • Detail
  • Sigma

  • (27029)  Sodiumcholatehydrate  ≥97.0% (dried material, NT)

  • 206986-87-0

  • 27029-500G-F

  • 6,370.65CNY

  • Detail
  • Sigma

  • (C6445)  Sodiumcholatehydrate  BioXtra, ≥99%

  • 206986-87-0

  • C6445-10G

  • 526.50CNY

  • Detail
  • Sigma

  • (C6445)  Sodiumcholatehydrate  BioXtra, ≥99%

  • 206986-87-0

  • C6445-25G

  • 821.34CNY

  • Detail
  • Sigma

  • (C6445)  Sodiumcholatehydrate  BioXtra, ≥99%

  • 206986-87-0

  • C6445-100G

  • 2,109.51CNY

  • Detail
  • Sigma

  • (C6445)  Sodiumcholatehydrate  BioXtra, ≥99%

  • 206986-87-0

  • C6445-500G

  • 8,441.55CNY

  • Detail
  • Sigma

  • (C1254)  Sodiumcholatehydrate  from ox and/or sheep bile, ≥99%

  • 206986-87-0

  • C1254-25G

  • 506.38CNY

  • Detail
  • Sigma

  • (C1254)  Sodiumcholatehydrate  from ox and/or sheep bile, ≥99%

  • 206986-87-0

  • C1254-100G

  • 817.83CNY

  • Detail
  • Sigma

  • (C1254)  Sodiumcholatehydrate  from ox and/or sheep bile, ≥99%

  • 206986-87-0

  • C1254-500G

  • 3,671.46CNY

  • Detail
  • Sigma

  • (C1254)  Sodiumcholatehydrate  from ox and/or sheep bile, ≥99%

  • 206986-87-0

  • C1254-1KG

  • 6,800.04CNY

  • Detail

206986-87-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name sodium,(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate,hydrate

1.2 Other means of identification

Product number -
Other names Cholalic acid sodium salt

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:206986-87-0 SDS

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