20705-39-9Relevant articles and documents
EFFETS DE CRYPTANDS ET ACTIVATION DE BASES-Va ACTION DES HYDRURES ALCALINS SUR LES ACIDES FAIBLES-II. ALKYLATION DES ANIONS OBTENUS
Pasquini, M. A.,Goaller, R. Le,Pierre, J.L.
, p. 1223 - 1226 (2007/10/02)
Phenoxides, alkoxides and potassium amidates generated by KH in THF or benzene at room temperature are easily alkylated in the presence of catalytic quantities of crytand, without affecting addition-elimination ratios.Thus, Williamson and Gabriel syntheses, as well as the alkylation of secondary amines, occur readily in mild conditions.