207122-47-2

Upstream product

• 207122-40-5 1-triisopropylsilanyloxy-4-(2-triisopropylsilanyloxy-ethyl)-benzene 
• 243641-04-5 methyl 2-(4-(triisopropylsilyloxy)phenyl)acetate 
• 13154-24-0 triisopropylsilyl chloride 
• 14199-15-6 Methyl 4-hydroxyphenylacetate 
• 156-38-7 4-hydroxyphenylacetate 
• 17138-28-2 (4-hydroxy-phenyl)-acetic acid ethyl ester 

Downstream Products

• 1331740-74-9 4-(2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethyl)phenyl sulfamate 

Relevant academic research and scientific papers

Seven-membered fused ring compound and organic photovoltaic cell

The invention discloses a seven-membered fused ring compound shown as a formula (I) and an organic photovoltaic cell containing the seven-membered fused ring compound. When the seven-membered fused ring compound is used as a non-fullerene organic electron acceptor material, a relatively environment-friendly chlorine-free solvent can be used for coating in the manufacturing process of an organic photovoltaic cell, and meanwhile, the high energy conversion efficiency (PCE) of the organic photovoltaic cell can be maintained;.

A novel, chemoselective and efficient microwave-assisted deprotection of silyl ethers with Selectfluor

A novel microwave-assisted, chemoselective and efficient method for the cleavage of silyl ethers (aliphatic and aromatic) catalyzed by Selectfluor is reported. A wide range of TBS-, TIPS-, and TBDPS-protected alkyl silyl ethers can be chemoselectively cleaved in high yield in the presence of aryl silyl ethers. The chemoselective deprotection of phenolic TBS ethers, and not the TIPS- or TBDPS-protected phenolic ethers, and the deprotection of silyl esters were also achieved under these reaction conditions. In addition, the transetherification and etherification of benzylic hydroxy groups in alcoholic solvents is observed.

The chemoselective and efficient deprotection of silyl ethers using trimethylsilyl bromide

An efficient and chemoselective cleavage of silyl ethers (primary, secondary and aromatic) by using catalytic quantities of trimethylsilyl bromide (TMSBr) in methanol is reported. A wide range of alkyl silyl ethers such as TBS, TIPS, and TBDPS can be chemoselectively cleaved in high yield in the presence of aryl silyl ethers. The deprotection of silyl esters was also achieved employing catalytic quantities of TMSBr. The Royal Society of Chemistry 2008.

Structure-activity relationships of the antimalarial agent artemisinin. 8. Design, synthesis, and CoMFA studies toward the development of artemisinin-based drugs against leishmaniasis and malaria

Artemisinin (1) and its analogues have been well studied for their antimalarial activity. Here we present the antimalarial activity of some novel C-9-modified artemisinin analogues synthesized using artemisitene as the key intermediate. Further, antileish

ARTEMISININ-BASED PEROXIDE COMPOUNDS AS BROAD SPECTRUM ANTI-INFECTIVE AGENTS

Described herein is the synthesis, bioassay results and utility of new C-9 and C-10 substituted artemisinin derivatives with easily functionalizable groups attached to the artemisinin skeleton through carbon chain or heteroatoms. Described also is the demonstration of this class of compounds for their broad-spectrum anti-parasitic activity. Certain of these analogs possess noticeable cytotoxicity deliberately focused on treatment of cancerous diseases.

Selective deprotection of alkyl vs. aryl silyl ethers

Alkyl silyl ethers, in particular t-butyldimethylsilyl derivatives, can be selectively cleaved in high yields over aryl silyl ethers using small percentage of I2 in MeOH at ambient temperatures.