207127-03-5Relevant articles and documents
Synthesis of protected, chiral α,α-disubstituted α-amino acids via a Beckmann rearrangement
Frutos, Rogelio P.,Spero, Denice M.
, p. 2475 - 2478 (1998)
The synthesis of chiral, nonracemic, fully protected α,α- disubstituted α-amino acids via the Beckmann rearrangement of tosylated oximes 1 is described. The desired amino acids were obtained in good yields with excellent enantioselectivities in relatively few steps.