207223-26-5Relevant academic research and scientific papers
Enantioselective synthesis of α-hydroxy γ-butyrolactones from an ephedrine-derived morpholine-dione
Pansare, Sunil V,Shinkre, Bidhan A,Bhattacharyya, Annyt
, p. 8985 - 8991 (2007/10/03)
An ephedrine-derived morpholine dione is employed in the enantioselective synthesis of (S)-α-hydroxy γ,γ-dimethyl-γ-butyrolactone and (S)-α-hydroxy γ-butyrolactone. A one-pot alkylation/allylation protocol for the stereoselective conversion of the dione to 2-alkyl-2-allyl morpholinones, key intermediates for α-alkyl-α-hydroxy-γ-butyrolactones, is described.
Asymmetric synthesis of α-alkyl-α-hydroxy-γ-butyrolactones
Pansare, Sunil V.,Jain, Rajendra P.,Ravi, R. Gnana
, p. 3103 - 3106 (2007/10/03)
A new enantioselective approach to α-alkyl-α-hydroxy-γ-butyrolactones employing (1R,2S)-ephedrine-derived chiral allyl morpholinones as starting materials is described.
