207227-14-3Relevant academic research and scientific papers
An enantioselective synthesis of (+)-pseudohygroline
Enierga, Gina,Hockless, David C. R.,Perlmutter, Patrick,Rose, Mark,Sjoeberg, Stefan,Wong, Katie
, p. 2813 - 2814 (1998)
The enantioselective synthesis of (+)-pseudohygroline (3), employing a highly diastereoselective ring closure as a key step, has been achieved in seven steps from readily available protected lactaldehyde (6).
Intramolecular amidomercurations under allylic control: A stereoselective synthesis of (+)-pseudohygroline and (+)-3-hydroxypyrrolizidine
Enierga, Gina,Espiritu, Maria,Perlmutter, Patrick,Pham, Ngoc,Rose, Mark,Sjoeberg, Stefan,Thienthong, Neeranat,Wong, Katie
, p. 597 - 604 (2007/10/03)
The diastereoselectivity of intramolecular amidomercurations can be reversed by altering the remote allylic substituent of ω-alkenylcarbamates. This methodology has been applied to the synthesis of (+)-pseudohygroline and (+)-3-hydroxypyrrolizidine.
