207276-53-7Relevant academic research and scientific papers
Stereoselective synthesis of alcohols; LII: Synthesis of the C-10 to C- 18 part of the mycalamides
Breitfelder, Steffen,Schlapbach, Achim,Hoffmann, Reinhard W.
, p. 468 - 478 (2007/10/03)
A synthesis of the right hand fragment, C-10 to C-18, of mycalamide B is described using three stereogenic centers of D-arabinose. This synthesis profits from the peculiar conformational properties of the trioxa-cis- decalin ring system, which has a high tendency to populate an O-proximal conformation. The described synthesis supersedes earlier attempts to reach the right hand fragment of the mycalamides from the C-10-epi-series.
