207277-47-2Relevant academic research and scientific papers
4-[ω-[4-Arylpiperazin-1-yl]alkoxy]phenylimidazo[1,2-a]pyridine derivatives: Fluorescent high-affinity dopamine D3 receptor ligands as potential probes for receptor visualization
Leopoldo, Marcello,Lacivita, Enza,Passafiume, Elena,Contino, Marialessandra,Colabufo, Nicola A.,Berardi, Francesco,Perrone, Roberto
, p. 5043 - 5047 (2008/03/12)
Sixteen long-chain arylpiperazines bearing the fluorescent moiety 2-phenylimidazo[1,2-a]pyridine were synthesized as fluorescent dopamine D 3 receptors ligands (385 nM i 3 compounds 15a and
Substituted phenoxyalkylpiperazines as dopamine d3 receptor ligands
Laszlovszky,Acs,Kiss,Domany
, p. 287 - 289 (2007/10/03)
A novel series of potential antipsychotic agents were prepared by combination of condensed heterocycles containing bridgehead nitrogen with (2-methoxyphenyl)piperazine using phenoxyalkyl spacer of variable length. The affinity of the compounds was determined at rat cloned D3 and rat D2, 5-HT1A receptors by an vitro receptor binding assay. The D3 selectivity of the compounds was calculated from the Ki values.
