207279-31-0

Basic information

• Product Name: 4-(8-Bromo-[1,7]naphthyridin-6-yl)-benzoic acid
• Synonyms: 4-(8-Bromo-[1,7]naphthyridin-6-yl)-benzoic acid
• CAS NO: 207279-31-0
• Molecular Formula: C₁₅H₉BrN₂O₂
• Molecular Weight: 329.14816
• Product Categories: Heterocyclic Building Blocks
• Mol File: 207279-31-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(8-Bromo-[1,7]naphthyridin-6-yl)-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(8-Bromo-[1,7]naphthyridin-6-yl)-benzoic acid(207279-31-0)
• EPA Substance Registry System: 4-(8-Bromo-[1,7]naphthyridin-6-yl)-benzoic acid(207279-31-0)

Safety Data

• Hazardous Substances Data: 207279-31-0(Hazardous Substances Data)

Upstream product

• 207279-29-6 8-methoxy-1,7-naphthyridin-6-yl trifluoromethanesulfonate 
• 55716-28-4 8-methoxy-[1,7]naphthyridin-6-ylamine 
• 5912-34-5 2-cyano-pyridin-3-yl-acetonitrile 
• 14047-29-1 4-carboxyphenylboronic acid 
• 207279-30-9 6-(4-carboxyphenyl)-8-methoxy-1,7-naphthyridine 

Downstream Products

• 207279-12-7 6-(4-carboxyphenyl)-8-(4-benzo[c]furazanyl)-1,7-naphthyridine 
• 426268-06-6 RO-458,2640 

Relevant articles and documents

Synthesis of 4-(8-benzo[1,2,5]oxadiazol-5-yl-[1,7]naphthyridine-6-yl)-benzoic acid: A potent and selective phosphodiesterase type 4D inhibitor

The synthesis of a 6,8-disubstituted 1,7-naphthyridine 1 and its characterization as a potent and selective phosphodiesterase type 4D inhibitor (IC50=1.5nM) are described. The compound inhibited TNFα-release from human peripheral blood mononuclear cells and was orally active in a model of adjuvant-induced arthritis in rats.