20734-22-9

Usage

Uses

Used in Organic Synthesis:
2,5-Dibromopyridin-1-ium-1-olate is utilized as a reagent in organic synthesis for its ability to facilitate the formation of new carbon-carbon or carbon-heteroatom bonds in a variety of chemical reactions. Its unique structure allows it to act as a versatile intermediate in the synthesis of complex organic molecules.
Used in Pharmaceutical Preparation:
In the pharmaceutical industry, 2,5-Dibromopyridin-1-ium-1-olate serves as an important building block. It is employed in the preparation of various pharmaceuticals due to its potential to contribute to the development of novel drug molecules with specific therapeutic properties.
Used in Agrochemical Development:
Similarly, in agrochemicals, 2,5-Dibromopyridin-1-ium-1-olate is used as a key component in the synthesis of compounds that can be applied in agricultural settings to protect crops or enhance their growth, making it a valuable asset in the development of new agrochemical products.
Used in the Production of Fine Chemicals:
2,5-Dibromopyridin-1-ium-1-olate is also integral to the production of fine chemicals, where its unique properties can be harnessed to create specialty chemicals used in various industries, such as fragrances, dyes, or advanced materials.

Upstream product

• 624-28-2 2,5-dibromopyridine 

Downstream Products

• 2402-97-3 3-bromopyridine N-oxide 
• 221241-31-2 2,5-dibromo-4-nitropyridine 
• 221241-25-4 C₅H₂Br₂N₂O₃ 

Relevant academic research and scientific papers

Strategic Approach on N-Oxides in Gold Catalysis – A Case Study

An extensive kinetic study of selected key reactions of (oxidative) gold catalysis concentrates on the decrease of the catalytic activity due to inhibition of the gold(I) catalyst caused by pyridine derivatives that are obtained as by-products if N-oxides are applied as oxygen donors. The choice of the examined pyridine derivatives and their corresponding N-oxides has been made regardless of their commercial availability; particular attention has been paid to the practical benefit which up to now has been neglected in most of the reaction screenings. The test reactions were monitored by GC and 1H NMR spectroscopy. The received reaction constants provide information concerning a correlation between the electronic structure of the heterocycle and the catalytic activity. Based on the collected kinetic data, it was possible to develop a basic set of three N-oxides which have to be taken into account in further oxidative gold(I)-catalyzed reactions. (Figure presented.).

ANTI-FIBROTIC PYRIDINONES

This application relates to polycyclic compounds with a pyridinone or pyridinone derivative core including, substituted pyridinones, 5,6- and 6,6- bicyclic heterocycles and substituted pyridine-thiones. This application also discloses methods of preparing these polycyclic compounds, pharmaceutical compositions and medicaments comprising said compounds and methods to treat, prevent or diagnose diseases, disorders or conditions associated with fibrosis.

Magnesiation of pyridine N-oxides via iodine or bromine-magnesium exchange: A useful tool for functionalizing pyridine N-oxides

Iodo- or 2-bromopyridine N-oxides were readily magnesiated with i-PrMgCl ? LiCl via the iodine or bromine-magnesium exchange. The bromine adjacent to pyridine N-oxide (at the 2- or 6-position) can be regioselectively magnesiated in the presence of other position substituted halogens. This method was tested in various substituted pyridine N-oxide systems, and has been successfully applied to the total synthesis of caerulomycins E and A.