20735-15-3 Usage
Uses
Used in Pharmaceutical Industry:
1-Phenyl-2-butanamine hydrochloride is used as an active pharmaceutical ingredient for its stimulant properties, as it weakly mimics the signaling and stimulant properties of D-amphetamine. It can be utilized in the development of medications targeting various conditions that may benefit from stimulant effects.
Used in Forensic Applications:
In the forensic field, 1-Phenyl-2-butanamine hydrochloride is used for the analysis and identification of recreational drugs and their potential substitutes. Its presence can help in understanding the chemical composition and effects of new or emerging substances.
Used in Research Applications:
1-Phenyl-2-butanamine hydrochloride serves as a valuable research tool for studying the mechanisms of action, signaling pathways, and potential therapeutic applications of amphetamine-like compounds. It can be used to investigate the effects of these compounds on neurotransmitter transporters and their role in various neurological and psychiatric conditions.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 31, p. 824, 1988 DOI: 10.1021/jm00399a024
Check Digit Verification of cas no
The CAS Registry Mumber 20735-15-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,7,3 and 5 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 20735-15:
(7*2)+(6*0)+(5*7)+(4*3)+(3*5)+(2*1)+(1*5)=83
83 % 10 = 3
So 20735-15-3 is a valid CAS Registry Number.
20735-15-3Relevant academic research and scientific papers
A Reinvestigation of the Pictet-Gams Isoquinoline Synthesis. Part 2. Formation of Rearranged Isoquinolines: the Δ2-Oxazoline-Isoquinoline Transformation
Ardabilchi, Nasser,Fitton, Alan O.,Hadi, A. Hamid b. A.,Thompson, J. Robin
, p. 1710 - 1725 (2007/10/02)
Cyclisation of a series of 2-substituted 2-acylamino-1-arylalkan-1-ols using phosphorus pentaoxide in refluxing decalin is shown to lead to rearranged, i.e. 4-substituted, isoquinolines in addition to the anticipated 3-substituted isomers.The products arise largely via 5-phenyl-Δ2-oxazoline intermediates and the formation of the rearranged isoquionolines from these intermediates is fully discussed.The pathway is not substantially altered when 2-benzamido-1-methoxy-1-phenylalkanes are cyclised.
