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Codeine β-D-Glucuronide Triacetate Methyl Ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

20736-10-1

20736-10-1 Suppliers

This product is a nationally controlled contraband or patented product, and the Lookchem platform doesn't provide relevant sales information.

20736-10-1 Usage

Chemical Properties

Brown Solid

Uses

A protected metabolite of Codeine (C634075).

Check Digit Verification of cas no

The CAS Registry Mumber 20736-10-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,7,3 and 6 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 20736-10:
(7*2)+(6*0)+(5*7)+(4*3)+(3*6)+(2*1)+(1*0)=81
81 % 10 = 1
So 20736-10-1 is a valid CAS Registry Number.

20736-10-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl (2S,3S,4S,5R,6R)-6-[[(4S,4aR,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl]oxy]-3,4,5-triacetyloxyoxane-2-carboxylate

1.2 Other means of identification

Product number -
Other names 7,8-Didehydro-4,5|A-epoxy-3-methoxy-17-methylmorphinan-6|A-yl |A-D-Glucopyranosiduronic Acid 2,3,4-|(3)riacetate | notethyl | yenster

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:20736-10-1 SDS

20736-10-1Downstream Products

20736-10-1Relevant academic research and scientific papers

Analgesic and immunomodulatory effects of codeine and codeine 6-glucuronide

Srinivasan, Vinayak,Wielbo, Donna,Simpkins, James,Karlix, Janet,Sloan, Kenneth,Tebbett, Ian

, p. 296 - 300 (1996)

Purpose. The antinociceptive and immunosuppressive effects of codeine and codeine 6-glucuronide were determined in rats after intracerebroventricular administration. Methods. Codeine 6-glucuronide was synthesized using a modification of the Koenigs-Knorr reaction. A lipophilic intermediate formed during synthesis, methyl [codein-6-yl-2,3,4-tri-O-acetyl-β-D-glucopyranosid] uronate, was also tested. Morphine was used as a positive control to compare antinociceptive potencies of these compounds. Results. All compounds tested produced significant analgesic responses, as assessed by the tail flick model. Additionally, codeine 6-glucuronide showed significantly less immunosuppressive effects than codeine in vitro. Conclusions. We conclude that codeine 6-glucuronide and related compounds may have clinical benefit in the treatment of pain in immune compromised patients.

A synthesis of morphine-6-glucuronide

Lacy, Christopher

, p. 3949 - 3950 (1995)

A practical synthesis of morphine-6-glucuronide from 3-acetylmorphine and methyl 2α-bromo-3,4,5-tri-O-acetylglucuronate is described. Similar syntheses of codeine-6-glucuronide, codeine-6-glucoside and morphine-6-glucoside are also documented.

Selective synthesis of both isomers of morphine 6-β-D-glucuronide and their analogs

Rukhman, Igor,Yudovich, Lev,Nisnevich, Gennadiy,Gutman, Arie L

, p. 1083 - 1092 (2007/10/03)

A stereoselective synthesis of both isomers of the pharmaceutically important morphine 6-β-D-glucuronide (M6G) and its analogs was developed. The method is based on the use of ZnBr2 for the key coupling reaction. It was shown that the α/β stere