207405-67-2

Basic information

• Product Name: 8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-[(phenylmethyl)amino]-, 1,1-dimethylethyl ester, (3-endo)-
• CAS NO: 207405-67-2
• Molecular Formula: C19H28N2O2
• Molecular Weight: 316.444
• Mol File: 207405-67-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-[(phenylmethyl)amino]-, 1,1-dimethylethyl ester, (3-endo)-(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-[(phenylmethyl)amino]-, 1,1-dimethylethyl ester, (3-endo)-(207405-67-2)
• EPA Substance Registry System: 8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-[(phenylmethyl)amino]-, 1,1-dimethylethyl ester, (3-endo)-(207405-67-2)

Safety Data

• Hazardous Substances Data: 207405-67-2(Hazardous Substances Data)

Upstream product

• 185099-67-6 N-Boc-nortropinone 
• 100-46-9 benzylamine 
• 185099-67-6 Boc-tropinone 

Downstream Products

• 716359-02-3 endo-tert-butyl (1R,5S)-3-[(2-amino-4-fluorophenyl)amino]-8-azabicyclo[3.2.1]octane-8-carboxylate 
• 716359-00-1 endo-tert-butyl (1R,5S)-3-{[2-amino-4-(methylsulfonyl)phenyl]amino}-8-azabicyclo[3.2.1]octane-8-carboxylate 
• 716359-01-2 endo-tert-butyl (1R,5S)-3-[(4-fluoro-2-nifrophenyl)amino]-8-azabicyclo[3.2.1]octane-8-carboxylate 
• 716358-99-5 endo-tert-butyl (1R,5S)-3-{[4-(methylsulfonyl)-2-nitrophenyl]amino}-8-azabicyclo[3.2.1]octane-8-carboxylate 
• 280762-27-8 C₁₄H₁₇N₃ 
• 280762-13-2 endo-tert-butyl 3-[(2-aminophenyl)amino]-8-azabicyclo[3.2.1]octane-8-carboxylate 
• 280762-06-3 endo-tert-butyl 3-[(2-nitrophenyl)amino]-8-azabicyclo[3.2.1]octane-8-carboxylate 
• 207405-68-3 tert-butyl 3-endo-amino-8-azabicyclo[3.2.1]octane-8-carboxylate 

Relevant articles and documents

1-(3-AMINOPROPYL) SUBSTITUTED CYCLIC AMINE COMPOUNDS, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

Provided are 1-(3-aminopropyl) substituted cyclic amine compounds as represented by formula (I), pharmaceutically acceptable salts, enantiomers, diastereoisomers, racemates and mixtures thereof, and a method of synthesizing said 1-(3-aminopropyl) substituted cyclic amine compounds by using aromatic heterocyclic formaldehyde as raw material. Said compounds can be used as CCR 5 antagonist for the treatment of HIV infection.

PIPERAZINO DERIVATIVES AS NEUROKININ ANTAGONISTS

The invention relates to compounds of formula (I) wherein Z, Rc, y, m, u, Ar2, n, X, Rc', l and Ar2 are as described herein. These compounds are neurokinin antagonists. These compounds are useful in the treatment of chronic airway diseases such as asthma.