207409-21-0

Basic information

• Product Name: 8-((tertbutyldimethylsilyl)oxy)-1-phenyloct-4-yn-3-ol
• Synonyms: 8-((tertbutyldimethylsilyl)oxy)-1-phenyloct-4-yn-3-ol
• CAS NO: 207409-21-0
• Molecular Weight: 332.558
• Mol File: 207409-21-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 8-((tertbutyldimethylsilyl)oxy)-1-phenyloct-4-yn-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 8-((tertbutyldimethylsilyl)oxy)-1-phenyloct-4-yn-3-ol(207409-21-0)
• EPA Substance Registry System: 8-((tertbutyldimethylsilyl)oxy)-1-phenyloct-4-yn-3-ol(207409-21-0)

Safety Data

• Hazardous Substances Data: 207409-21-0(Hazardous Substances Data)

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 61362-77-4 5-[tert-butyldimethylsilyloxy]pent-1-yne 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 5390-04-5 pent-1-yn-5-ol 

Downstream Products

• 1208341-71-2 (E)-8-(tert-butyldimethylsilyloxy)-1-phenyloct-4-en-3-ol 
• 1067623-61-3 12,12,13,13-tetramethyl-5-phenethyl-2,4,11-trioxa-12-silatetradec-6-yne 
• 207409-33-4 Carbonic acid (Z)-6-(tert-butyl-dimethyl-silanyloxy)-1-phenethyl-hex-2-enyl ester methyl ester 
• 207409-39-0 Carbonic acid (Z)-6-hydroxy-1-phenethyl-hex-2-enyl ester methyl ester 

Relevant articles and documents

Regioselective cyclizations utilizing a gold-catalyzed [3,3] propargyl ester rearrangement

Switch-Au-roo: A new strategy for the regioselective synthesis of unsaturated carbocycles by chemoselective activation of a Rauhut-Currier zwitterion surrogate, formed from the Au-catalyzed [3,3] sigmatropic rearrangement of propargylic esters, has been achieved. By reversing the regiochemistry of the propargyl ester the synthesis of either the endo- or exocyclic enones is feasible.

Improved procedure for the synthesis of gem-diiodoalkanes by the alkylation of diiodomethane. Scope and limitations

(Chemical Equation Presented) Functionalized gem-diiodoalkanes are obtained in good to excellent yields by employing a convenient modified procedure for the alkylation of NaCHI2 with alkyl iodides. Complete conversion to the diiodide is reliably obtained, avoiding a problematic separation of any remaining iodide starting material. Functional group tolerance toward olefins, acetals, ethers and silyl ethers, carbamates, and hindered esters is demonstrated. The use of an excess of LiCHI2 allows complete conversion of allyl and benzyl bromides with minimal elimination from the diiodide product.