207446-89-7 Usage
Description
Arteannuin L is a sesquiterpene lactone compound derived from the traditional Chinese medicinal herb Artemisia annua. It is known for its significant anti-malarial activity, particularly against Plasmodium falciparum, the parasite responsible for the most lethal form of malaria. Arteannuin L inhibits the growth of the parasite at multiple stages of its life cycle, making it a promising candidate for the development of new anti-malarial drugs. Furthermore, it has also demonstrated anti-inflammatory and anticancer properties, expanding its potential for therapeutic applications beyond malaria treatment.
Uses
Used in Pharmaceutical Industry:
Arteannuin L is used as an anti-malarial agent for its significant activity against Plasmodium falciparum, the parasite responsible for the most lethal form of malaria. It inhibits the growth of the parasite at multiple stages of its life cycle, offering a promising solution for the development of new anti-malarial drugs.
Used in Anti-inflammatory Applications:
Arteannuin L is used as an anti-inflammatory agent due to its ability to reduce inflammation, which can be beneficial in treating various inflammatory conditions.
Used in Anticancer Applications:
Arteannuin L is used as an anticancer agent for its potential to combat cancer cells. Its anticancer properties make it a candidate for further research and development in the field of oncology.
Used in Drug Development:
Arteannuin L is used in the development of new drugs for its multifaceted therapeutic potential, including anti-malarial, anti-inflammatory, and anticancer properties. Its ability to target multiple stages of the Plasmodium falciparum life cycle and its additional health benefits make it a valuable compound for creating innovative treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 207446-89-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,7,4,4 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 207446-89:
(8*2)+(7*0)+(6*7)+(5*4)+(4*4)+(3*6)+(2*8)+(1*9)=137
137 % 10 = 7
So 207446-89-7 is a valid CAS Registry Number.
207446-89-7Relevant articles and documents
Structure elucidation of arteannuin O, a novel cadinane diol from Artemisia annua, and the synthesis of arteannuins K, L, M and O
Sy, Lai-King,Cheung, Kung-Kai,Zhu, Nian-Yong,Brown, Geoffrey D
, p. 8481 - 8493 (2007/10/03)
The novel cadinane diol, arteannuin O (1), has been obtained from Artemisia annua and its structure has been established by 2D NMR and X-ray crystallography. A reconstructive synthesis of arteannuin O from artemisinin is described, which also yields the natural products arteannuin K and arteannuin L. Mechanistic considerations have led to the conclusion that the stereochemistry of the 5-hydroxyl group was wrongly assigned when arteannuins K, L and M were first reported as natural products. This was confirmed by derivatization of synthetic arteannuins K, L and M as their Mosher esters.