2074615-22-6Relevant academic research and scientific papers
Efficient synthesis of substances related to cinacalcet hydrochloride via heck coupling
Lei, Fan,Qu, Boyi,Li, Xiaolong,Guo, Li,Guan, Mei,Hai, Li,Jin, Hui,Wu, Yong
, p. 2879 - 2885 (2014)
Efficient synthetic methods to process substances related to cinacalcet hydrochloride 1, generated during the preparation, were described. The compounds were identified as [1-(7,8-dihydro-naphthalen-1-yl)-ethyl]-[3-(3- trifluoromethyl-phenyl)-propyl]-amine hydrochloride 2,[1-(5,6,7,8-tetrahydro- naphthalen-1-yl)-ethyl]-[3-(3-trifluoromethyl-phenyl)-propyl]-amine hydrochloride 3 and [1-(naphthalen-2-yl)-ethyl]-[3-(3-trifluoromethyl-phenyl)- propyl]-amine hydrochloride 4. All were prepared from commercially available materials in several linear steps and characterized by their respective spectral data.
