207557-90-2

Upstream product

• 926-02-3 tert-butyl vinyl ether 

Downstream Products

• 207557-99-1 (4S,6S)-4-tert-Butoxy-6-((R)-methoxycarbonyl-phenyl-methoxy)-5,6-dihydro-4H-pyran-2-carboxylic acid methyl ester 
• 543741-95-3 4-tert-butoxy-6-(tert-butoxycarbonyl-phenyl-methoxy)-6-ethyl-5-methyl-5,6-dihydro-4H-pyran-2-carboxylic acid methyl ester 
• 725258-04-8 (2R,4R)-4-(tert-butoxy)-2-[(4R)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-3,4-dihydro-2H-pyran-6-carboxylic acid methyl ester 
• 725258-05-9 (2S,4S)-4-(tert-butoxy)-2-[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]-3,4-dihydro-2H-pyran-6-carboxylic acid methyl ester 
• 725258-06-0 (2R,4R)-4-(tert-butoxy)-2-[(4R,5S)-4-methyl-2-oxo-5-phenyl-1,3-oxazolidin-3-yl]-3,4-dihydro-2H-pyran-6-carboxylic acid methyl ester 
• 207558-12-1 (4S,6S)-6-Benzyloxymethyl-4-tert-butoxy-tetrahydro-pyran-2-one 
• 207558-08-5 (R)-2-((2R,4R,6R)-4-tert-Butoxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-2-phenyl-ethanol 
• 207558-06-3 (2R,4R,6R)-4-tert-Butoxy-6-((R)-methoxycarbonyl-phenyl-methoxy)-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 207558-09-6 (2R,4R,6R)-2-Benzyloxymethyl-6-((R)-2-benzyloxy-1-phenyl-ethoxy)-4-tert-butoxy-tetrahydro-pyran 

Relevant academic research and scientific papers

An improved dienophile-induced access to enantiopure 2,4-dideoxysugar lactones via hetero Diels-Alder reaction: Synthesis of the (+)-lactone moiety of compactin

Polystereocontrolled access to 4-type heterocycloadducts was consistently improved by using a new 4-oxy-substituted 1-oxabutadiene, methyl (E)-tert-butoxymethylenepyruvate (1c). Obtained in both enantiomeric forms with high diastereomerical purity, these adducts led to diprotected 2,4- dideoxyglucose 10 and -gluconolactone 12 in both L and D series in high yields. Epimerization of (-)-12 via intramolecular Mitsunobu inversion gave a straightforward access to the lactone moiety (+)-16 of compactin.