207595-80-0Relevant academic research and scientific papers
A new, practical and efficient method for protecting alcohols as tert-butyl ethers
Barge, Alessandro,Occhiato, Ernesto G.,Prandi, Cristina,Scarpi, Dina,Tabasso, Silvia,Venturello, Paolo
, p. 812 - 816 (2010)
A new method for protecting alcohols as tert-butyl ethers is reported. The reaction is performed in tert-butyl acetate in the presence of a catalytic amount of HClO4. The process is extremely efficient and primary and secondary alcohols as well as diols are protected under very mild conditions. Remarkably, tert-butyl acetate can be easily recovered after the workup of the reaction and recycled.
