20763-22-8Relevant articles and documents
Synthesis, characterization and catalytic behaviour of a palladium complex bearing a hydroxy-functionalized N-heterocyclic carbene ligand
Mariconda, Annaluisa,Grisi, Fabia,Costabile, Chiara,Falcone, Salvatore,Bertolasi, Valerio,Longo, Pasquale
, p. 762 - 769 (2014/02/14)
The synthesis of a new stable palladium(II) complex (3) featuring an unsymmetrical substituted N-heterocyclic carbene (NHC) ligand with a pendant hydroxy-functionalized group was successfully accomplished via transmetalation of the corresponding bis-NHC silver(I) complex (2). Solid-state structures of both 2 and 3 were determined by single-crystal X-ray diffraction. The catalytic behaviour of 3 in the direct regioselective arylation of furan and thiophene derivatives by using challenging aryl halides was studied, revealing that 3 was capable of promoting these environmentally attractive coupling reactions to afford arylated heterocycles in moderate to good yields.
N-heterocyclic carbenes: Useful ligands for the palladium-catalysed direct C5 arylation of heteroaromatics with aryl bromides or electron-deficient aryl chlorides
Ozdemir, Ismail,Goek, Yetkin,Oezeroglu, Oezlem,Kaloglu, Murat,Doucet, Henri,Bruneau, Christian
experimental part, p. 1798 - 1805 (2010/08/13)
New Pd-N-heterocyclic carbene complexes have been prepared and employed for palladium-catalysed direct arylation of heteroaromatic derivatives by using aryl halides. These catalyst precursors promote the coupling of challenging aryl halides such, as deactivated or congested aryl bromides and also activated aryl chlorides. This procedure employs only 1 mol-% of an air-stable palladium complex. This is a practical advantage over the procedures that employ palladium attached to air-sensitive phosphane ligands, which are often used to promote the coupling of such, aryl halides.
