20763-27-3

Usage

Bicyclic structure

1-Methyl-1-azoniabicyclo[3.2.0]heptane has a unique ring structure consisting of two fused rings.

Positively charged nitrogen atom

The compound contains a quaternary nitrogen atom with a positive charge.

Phase-transfer catalyst

1-Methyl-1-azoniabicyclo[3.2.0]heptane is commonly used as a phase-transfer catalyst in organic synthesis.

Various reactions

The compound has been used in a range of reactions, including alkylation, acetylation, and nucleophilic substitution reactions.

Stable and versatile reagent

1-Methyl-1-azoniabicyclo[3.2.0]heptane is a stable and versatile reagent that facilitates the transfer of ions between immiscible phases.

Commercially available

The compound is readily available for purchase.

Effective catalyst

1-Methyl-1-azoniabicyclo[3.2.0]heptane has been found to be an effective catalyst in several organic transformations.

Upstream product

• 19065-49-7 rac-4-Hydroxy-1-methylazepan 

Relevant academic research and scientific papers

Ring-rearrangement during the Mitsunobu alkylation of phthalazinones and indazolols

The Mitsunobu alkylation of substituted phthalazinones and indazolols with cyclic hydroxy- and hydroxymethyl-substituted amines was investigated. In addition to the expected derivatives ring-narrowed and ring-enlarged rearrangement products were isolated and characterized by NMR spectroscopy. The occurence of these products can be explained by the existence of a bicyclic intermediate. The results of the reaction of phthalazinones with optically active amine compounds show a stereospecific reaction mechanism. The reaction of the phthalazinones leads to N-substituted products, while in the case of the indazolols O-substituted derivatives were isolated. A postulated bicyclic intermediate, 1-methyl-1-azoniabicyclo[3.2.0]heptane, was synthesized as chloride. VCH Verlagsgesellschaft mbH, 1996.

HETEROCYCLIC ETHERS DERIVED FROM 6,11-DIHYDRODIBENZOTHIEPIN-11-OLS AND 4,9-DIHYDROTHIENO-2-BENZOTHIEPIN-4-OL; A NEW SERIES OF POTENTIAL ANTIDEPRESSANTS AND ANTIHISTAMINE AGENTS

Reactions of 11-chloro-6,11-dihydrodibenzothiepin and methanesulfonates of 6,11-dihydrodibenzothiepin-11-ol (I), its 2-methyl derivative II and 4,9-dihydrothieno-2-benzothiepin-4-ol (III) with 1-methylpiperidin-4-ol, 1-methylperhydroazepin-4-ol (XIX), and tropine gave the ethers V-X.Their methanesulfonates were pharmacologically tested and showed antireserpine, anticataleptic, and antihistamine activities of various degree.The most active compounds were the ethers V and VI.