20763-50-2

Upstream product

• 1131-18-6 1-Phenyl-3-methyl-5-aminopyrazole 

Downstream Products

• 123605-53-8 6-Biphenyl-4-yl-3-methyl-1-phenyl-1,5-dihydro-pyrazolo[4,3-b][1,4]thiazine 
• 123605-58-3 Bis(7-methyl-3-(4-biphenyl)-5-phenylpyrazolo<4.5-b>-2H-1,4-thiazine-2-yl) 
• 123605-51-6 5-Amino-4-(ω-phenacetylthio)-3-methyl-1-phenylpyrazole 
• 123605-54-9 6-(4-Chloro-phenyl)-3-methyl-1-phenyl-1,5-dihydro-pyrazolo[4,3-b][1,4]thiazine 
• 123605-59-4 Bis(7-methyl-3-(4-chlorophenyl)-5-phenyl-pyrazolo<4.5-b>-2H-1,4-thiazine-2-yl) 
• 123605-52-7 5-Amino-4-(ω-<4-bromophenacetylthio>)-3-methyl-1-phenylpyrazole 
• 123605-57-2 Bis(7-methyl-3,5-diphenylpyrazolo<4.5-b>-2H-1,4-thiazine-2-yl) 

Relevant academic research and scientific papers

Hydrogen Peroxide-Mediated Rapid Room Temperature Metal-Free C(sp2)-H Thiocyanation of Amino Pyrazoles, Amino Uracils, and Enamines

A rapid metal-and additive-free room temperature method for C(sp2)-H thiocyanation of aminopyrazoles, aminoisoxazole, aminoisothiazole, amino uracils, and aliphatic enamines has been developed in an aqueous medium using hydrogen peroxide as a benign oxidant and ammonium thiocyanate as a thiocyanating agent. On the other hand, the reaction of hydrogen peroxide and ammonium thiocyanate followed by one-pot addition of NaOH provides the corresponding disulfides in the case of amino azoles, and pyrimidine-fused 2-amino thiazoles were observed in the case of aminouracils. The salient features of this method are the use of an eco-friendly oxidant, reaction tunability to access different products, wide substrate scope, and good to very good yields.