207849-82-9Relevant articles and documents
Novel potent 5-HT1F receptor agonists: Structure-activity studies of a series of substituted N-[3-(1-methyl-4-piperidinyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]amides
Filla, Sandra A.,Mathes, Brian M.,Johnson, Kirk W.,Phebus, Lee A.,Cohen, Marlene L.,Nelson, David L.,Zgombick, John M.,Erickson, Jon A.,Schenck, Kathryn W.,Wainscott, David B.,Branchek, Theresa A.,Schaus, John M.
, p. 3060 - 3071 (2007/10/03)
Compound 1a (LY334370), a selective 5-HT1F receptor agonist (SSOFRA), inhibited dural inflammation in the neurogenic plasma protein extravasation model of migraine and demonstrated clinical efficacy for the acute treatment of migraine. Although