207864-22-0Relevant articles and documents
A general electrochemical strategy for the Sandmeyer reaction
Liu, Qianyi,Sun, Beiqi,Liu, Zheng,Kao, Yi,Dong, Bo-Wei,Jiang, Shang-Da,Li, Feng,Liu, Guoquan,Yang, Yang,Mo, Fanyang
, p. 8731 - 8737 (2018/12/10)
Herein we report a general electrochemical strategy for the Sandmeyer reaction. Using electricity as the driving force, this protocol employs a simple and inexpensive halogen source, such as NBS, CBrCl3, CH2I2, CCl4, LiCl and NaBr for the halogenation of aryl diazonium salts. In addition, we found that these electrochemical reactions could be performed using anilines as the starting material in a one-pot fashion. Furthermore, the practicality of this process was demonstrated in the multigram scale synthesis of aryl halides using highly inexpensive graphite as the electrode. A series of detailed mechanism studies have been performed, including radical clock and radical scavenger study, cyclic voltammetry analysis and in situ electron paramagnetic resonance (EPR) analysis.
Facile synthesis of para-[18F]fluorohippurate via iodonium ylide-mediated radiofluorination for PET renography
Nkepang, Gregory N.,Hedrick, Andria F.,Awasthi, Vibhudutta,Gali, Hariprasad
, p. 479 - 483 (2016/01/09)
para-[18F]fluorohippurate ([18F]PFH) is a renal tubular agent suitable for conducting positron emission tomography (PET) renography. [18F]PFH is currently synthesized by a four-step two-pot procedure utilizing a classical
Evaluation of the radiolabeled boronic acid-based FAP Inhibitor MIP-1232 for atherosclerotic plaque imaging
Meletta, Romana,Herde, Adrienne M??ller,Chiotellis, Aristeidis,Isa, Malsor,Rancic, Zoran,Borel, Nicole,Ametamey, Simon M.,Kr??mer, Stefanie D.,Schibli, Roger
, p. 2081 - 2099 (2015/03/05)
Research towards the non-invasive imaging of atherosclerotic plaques is of high clinical priority as early recognition of vulnerable plaques may reduce the incidence of cardiovascular events. The fibroblast activation protein alpha (FAP) was recently prop
Synthesis of some 2,2′:6′,2″-terpyridines disubstituted in positions 6 and 6″ with head-to-tail oriented amino acids and dipeptides: A simple entry to a reversible inducer of folding in amino acid sequences
Annunziata, Rita,Benaglia, Maurizio,Puglisi, Alessandra,Raimondi, Laura,Cozzi, Franco
supporting information; experimental part, p. 3976 - 3983 (2009/04/10)
The 2,2′:6′,2″-terpyridine scaffold has been identified as a conformationally discrete structural element potentially capable of inducing reversible folding in substituents, attached through suitable spacers to its 6,6″-positions, by metal complexation/de
An efficient one-pot synthesis of hippuric acid ethyl ester derivatives
Conway, Samuel C.,Perni, Robert B.
, p. 1539 - 1545 (2007/10/03)
A rapid, one-pot procedure is described for the preparation of the ethyl esters of a number of ring-substituted N-benzoyl glycine (hippuric acid) derivatives from readily-available starling materials.