20788-17-4Relevant articles and documents
Room temperature clickable coupling electron deficient amines with sterically hindered carboxylic acids for the construction of amides
Liu, Jing,Wang, Shi-Meng,Qin, Hua-Li
, (2020)
A method for the synthesis of difficult-to-access amides was developed through the coupling of sterically hindered carboxylic acids and electron deficient amines via SO2F2-mediated dehydration. The method feathers with broad substrate scope, mild conditions, excellent functional group compatibility and high yields.